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- Which of the following statements is TRUE about cholesterol biosynthesis? O NADPH is needed to form mevalonate. O Cholesterol is composed of 30 carbon atoms. HMG-CoA lyase catalyzes the committed step. Five molecules of isopentyl pyrophosphate condense to form squalene.v Hydroxy methyl glutaryl coA Match the following metabolites with the correct metabolic pathway v Propionyl-CoA A. Kreb's cycle v Dihydroxy acetone phosphate B. Soluble fiber fermenta v succinyl co-A C. Cholesterol synthesis v Hydroxy methyl glutaryl coA D. glycolysis v Hydroxy-butyrate E. Beta oxidation6. The five steps involved in conversion of pyruvate to acetyl-CoA are listed below. For each step, list the enzyme(s) that are involved. 1. Decarboxylate pyruvate 2. Reduction of lipoic acid 3. Transfer of acetyl group to coenzyme A 4. Reoxidation of lipoic acid 5. Reoxidation of FADH2 → FAD
- Which of the following statements is TRUE about cholesterol biosynthesis? O NADH is needed to form mevalonate. O HMG-CoA lyase catalyzes the committed step. Six molecules of isopentyl pyrophosphate condense to form squalene. O Cholesterol is composed of 30 carbon atoms.Which of the following statements is TRUE about cholesterol biosynthesis? Group of answer choices HMG-CoA lyase catalyzes the committed step. Cholesterol is composed of 30 carbon atoms. NADH is needed to form mevalonate. Six molecules of isopentyl pyrophosphate condense to form squalene.In order to break the carbon-carbon bond of Acetyl-CoA in a way that does not harm the cell, citrate is produced in the TCA cycle. Explain how switching between 6-carbon, 5-carbon and 4-carbon metabolites eventually allows the two carbons of Acetyl-CoA to be converted to CO2 in a way that does not harm the cell.
- 1. Explain the Chemiosmotic theory with regard to ATP generation in oxidative phosphorylation. 2. Explain how Phosphorylase activation differs between the liver and the muscle. What is the role of Epinephrine in Glycogen metabolism. 3. List all the materials required for beta-oxidation of cholesterol from six-carbon intermediate Mevalonate.3) Indicate the order in which the metabolites in citric acid cycle are produced; acetyl CoA as 1 and oxaloacetate as 9. Metabolites in Citric Acid Cycle Order Enzyme involved in the formation of the metabolite Acetyl CoA 1 Oxaloacetate 9. Succinyl SCOA Fumarate Malate Citrate Succinate a-Ketoglutarate Isocitrate1. Consider the reaction: succinyl-CoA succinate H3C C H₂ a. What kind of reaction is being performed here? H³C C H₂ b. What enzyme performs this reaction? S-COA c. What cofactors, if any, are required for this reaction?
- 1) Tabulate the differences and/ or similarities of the different kinds of coenzymes and cofactors. Structure Source ATP SAM COA Retinal THF- tetrahydrofolate Vitamin K NAD, NADP FMN, FAD TPP PLP Adenosylcobalamin methylcobalamin and Function/ Role/ ImportancePharmaceuticals in a class called the statins inhibit theenzyme HMG-CoA reductase. What is the primary effect ofthis drug on patients?5. This question is about unsaturated fatty acid catabolism (B-oxidation). Compare and contrast how oleic and linoleic acid are completely degraded to acetyl-CoA.