Determine the symmetry group of the outer shell of the cross sec- tion of the human immunodeficiency virus (HIV) shown below. George V Kelvin
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- Unknown virus dsDNA contains 36% AT on a molar basis. What are the mole percentages of A, G and C respectively?Among the following structures, the drug that can be given orally against B-lactamase-producing strain: is: CO-H OCH COOH I COOH II NH2 HO COOH III IV COOH Oll ONone of the above OlI OIVHow many protein subunits would be present in a complex icosahedral virus particle with a triangulation (T) number of 8?
- A virus has a double-stranded RNA genome that has 2400 base-pairs. Of these, 35 % are G:C base-pairs. How many uracil nucleotides would be present in this virus?One of the key biological characteristics of SARS-COV-2, as well as several other viruses, is the presence of spike proteins that allow these viruses to penetrate host cells and cause infection. With your knowledge about proteins, which best explain how denaturating agents such as alcohol, and detergents become effective in battling against SARS-CoV 2? O Denaturating agents were able to destroy the spike protein by detaching it to the virus, losing its ability to infect host. Denaturating agents were able to kill the viruses such as SARS-COV-2, therefore, they will no longer able to infect the host Denaturating agents were able to hydrolyze the spike protein to produce free amino acids, therefore, the function of the protein is now lost. Denaturating agents were able to disrupt the native structure of the spike protein, losing its ability to infect host.Part B - Viral Classification: The Baltimore Scheme The Baltimore classification scheme is based on the relationship between the virus' genome and its mRNA. For the following choices, indicate which viruses would fall into each classification: 1) require reverse transcriptase to copy the information in their own genome to DNA; 2) can replicate and be transcribed in the same manner as the cell's own genetic material; and 3) a replicative form of DNA must be produced and is used for both replication and transcription. Drag and drop choices to the bins they describe. double-stranded DNA viruses Requires reverse transcriptase double-stranded RNA viruses retroviruses double-stranded DNA viruses that have an RNA intermediate Functions similarly to cell's own genetic material plus-strand RNA viruses minus-strand RNA viruses Reset Help plus-strand DNA viruses Uses a replicative form of DNA
- Compare the structure of an icosahedral capsid with that of a helical capsid. How do pentamers and hexamers associate to form a complete icosahedron? Which virus would have a longer helical capsid: a virus with a 7,200 base pair DNA genome or one with an 11,000 base ssRNA genome?Syn5 is a virus that infects photosynthetic bacteria belonging to the genus Synechococcus. The Syn5 virion is icosahedral (660 Å in diameter) with a short tail and an appendage called a horn. The horn is located on a vertex directly opposite the tail. Syn5 follows the typical five steps observed for most viruses when they multiply, and progeny viruses are released when the host lyses. The assembly of Syn5 virions involves several proteins, including capsid proteins, scaffolding proteins, a portal protein, a terminase, tail proteins, and horn proteins. To better understand the assembly of Syn5 virions, scientists used a type of microscopy called Zernike phase contrast electron cryotomography. This type of microscopy improves the contrast typically seen for conventional cryotomography. In their studies, the scientists observed several different developing virus particles in infected cells. The particles were: (1) 660 Å icosahedron containing DNA and having a tail; (2) 660 Å icosahedron…Can you please pick the right answer in each parentheses? The spike protein of SARS-CoV-2 is a carbohydrate-modified protein that ["bind the RNA genome of the virus", "", "is on the surface of the viral particle", ""] and plays a role in both ["replication of the viral genome", "recognition of host cell"] and ["packaging of viral genome for export", "fusion of viral envelope with host cell plasma membrane"] . Importantly, earlier work on spike proteins from other corona viruses showed that this molecule ["remarkable resistance to immune response", "shows remarkable conformational changes"] and only one of these served as a good antigen for vaccine development. A critical discovery in advancing the development of our current vaccines was determining what changes in the amino acid sequence would ["block degradation of the spike protein", "stabilize the conformation of the protein found on the viral particle"]. This…
- Neisseria gonorrhoeae what is the size mm (bx x 0.3 x 0.000001), how many base pairs does it have, how many encoding segments or genes, how many Non-encoding segements or pseudogenes, and how many structural RNAs?The relative amounts of each nitrogenous base are tabulated here for four different viruses. For each virus listed in the following table, indicate whether its genetic material is DNA or RNA and whether it is single stranded or double stranded. Explain your reasoning. Virus T C U G A I 0 12 9 12 9 II 23 16 0 16 23 III 34 42 0 18 39 IV 0 24 35 27 172.4 SARS-CoV-2 is mainly transmitted through respiratory droplets when an infected person sneezes, coughs, or talks. How might this relate to the size and/or structure of viruses?