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Describe the amino acid composition in terms of the general characteristics and comment on what the amino acid composition tells you about likely cellular location of the protein.

Describe the amino acid composition in terms of the general characteristics and comment on what the amino acid composition tells you about likely cellular location of the protein.

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 9QP: a. Compounds A, B, C, and D are known to be intermediates in the pathway for production of protein...
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Describe the amino acid composition in terms of the general characteristics and comment on what the amino acid composition tells you about likely cellular location of the protein.

PEPSTATS of EMBOSS_001 from 1 to 149 Molecular weight = 16949.07 Average Residue Weight = 113.752 Isoelectric Point = 9.5161 A280 Molar Extinction Coefficients = 31400 (reduced) 31525 (cystine bridges) A280 Extinction Coefficients 1mg/ml = 1.853 (reduced) Improbability of expression in inclusion bodies = 0.728 1.860 (cystine bridges) DayhoffStat 1.171 0.000 Residue A = Ala B = Asx C = Cys D = Asp E = Glu F = Phe G = Gly H = His I = Ile J = --- K = Lys L = Leu M = Met N = Asn 0 = P = Pro Q = Gln R = Arg S = Ser T = Thr U = --- V = Val W = Trp X = Xaa Y = Tyr Z = Glx Property Tiny Small Aliphatic Aromatic Non-polar Polar Charged Basic Acidic Number 15 0 3 5 2 9 6 2 9 0 4 12 9 STONONOMOGO 4 0 5 6 9 14 2 0 20 3 0 10 0 Residues (A+C+G+S+T) (A+I+L+V) (F+H+W+Y) Mole% 10.067 0.000 2.013 (B+D+E+H+K+R+Z) 3.356 1.342 6.040 4.027 1.342 6.040 0.000 2.685 Number 40 74 56 24 (A+C+F+G+I+L+M+P+V+W+Y) 101 48 22 15 7 (H+K+R) 8.054 6.040 2.685 0.000 3.356 (A+B+C+D+G+N+P+S+T+V) (B+D+E+Z) 4.027 6.040 9.396 1.342 0.000 13.423 2.013 0.000 6.711 0.000 (D+E+H+K+N+Q+R+S+T+Z) Residues = 149 Charge = 7.0 0.694 0.610 0.224 1.678 0.479 0.671 1.342 0.000 0.407 1.088 3.553 0.624 0.000 0.645 1.033 1.233 1.342 0.220 0.000 2.034 1.549 0.000 1.974 0.000 Mole% 26.846 49.664 37.584 16.107 67.785 32.215 14.765 10.067 4.698
Transcribed Image Text:PEPSTATS of EMBOSS_001 from 1 to 149 Molecular weight = 16949.07 Average Residue Weight = 113.752 Isoelectric Point = 9.5161 A280 Molar Extinction Coefficients = 31400 (reduced) 31525 (cystine bridges) A280 Extinction Coefficients 1mg/ml = 1.853 (reduced) Improbability of expression in inclusion bodies = 0.728 1.860 (cystine bridges) DayhoffStat 1.171 0.000 Residue A = Ala B = Asx C = Cys D = Asp E = Glu F = Phe G = Gly H = His I = Ile J = --- K = Lys L = Leu M = Met N = Asn 0 = P = Pro Q = Gln R = Arg S = Ser T = Thr U = --- V = Val W = Trp X = Xaa Y = Tyr Z = Glx Property Tiny Small Aliphatic Aromatic Non-polar Polar Charged Basic Acidic Number 15 0 3 5 2 9 6 2 9 0 4 12 9 STONONOMOGO 4 0 5 6 9 14 2 0 20 3 0 10 0 Residues (A+C+G+S+T) (A+I+L+V) (F+H+W+Y) Mole% 10.067 0.000 2.013 (B+D+E+H+K+R+Z) 3.356 1.342 6.040 4.027 1.342 6.040 0.000 2.685 Number 40 74 56 24 (A+C+F+G+I+L+M+P+V+W+Y) 101 48 22 15 7 (H+K+R) 8.054 6.040 2.685 0.000 3.356 (A+B+C+D+G+N+P+S+T+V) (B+D+E+Z) 4.027 6.040 9.396 1.342 0.000 13.423 2.013 0.000 6.711 0.000 (D+E+H+K+N+Q+R+S+T+Z) Residues = 149 Charge = 7.0 0.694 0.610 0.224 1.678 0.479 0.671 1.342 0.000 0.407 1.088 3.553 0.624 0.000 0.645 1.033 1.233 1.342 0.220 0.000 2.034 1.549 0.000 1.974 0.000 Mole% 26.846 49.664 37.584 16.107 67.785 32.215 14.765 10.067 4.698
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