Consider the reaction coordinate diagram shown below. X isisCatalysts lower the amountof energy required to reachthe transition state (theactivation energy)EnergyGround stateof reactantReaction coordinateAG ofcatalyzedreactionAG of thereactionGround stateof product; Y activation energy of catalyzed reaction; transition stateAG‡ of catalyzed reaction; transition statetransition state; activation energyAG‡ of uncatalyzed reaction; transition state

The above shown diagram is a reaction coordinate diagram. The free energy of the system is plotted…

Answered: Consider the reaction coordinate…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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the kinetics of an enzyme were analyzed in the absence of inhibitors, as well as in the presence of inhibitor A and inhibitor B. Using the given data below, construct or calculate the following (make sure the label graphs with appropriate axes and equations, and circle final answers) plot 1[S] as abscissa and 1/v as ordinate for both catalyzed reaction and reaction with inhibitor. Use the same graph for both plots Calculate the; Km of enzyme in the reaction without inhibitor Km of the enzyme in the reaction with inhibitor (A dnB) Vmax of the uninhibited reaction Vmax of the inhibited reaction (A and B) What kind of inhibitor (A and B) was added to the enzyme-catalyzed reaction? Explain in terms of changes in Km and Vmax
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Consider the reaction coordinate diagram shown below. X is is ;Y