Ch22. Carbonyl Alpha-Substitution Reactions - Keto-enol Tautomerism Carbonyl compounds react with base to create enolate - Halogenation - Alkylation onto a-Carbon of ketones and aldehydes 1.LDA (or NaH) 2.RX 1) LDA 2) Br

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Chapter1: Chemical Foundations
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Ch22. Carbonyl
Alpha-Substitution
Reactions
- Keto-enol Tautomerism
Carbonyl compounds react with base to create enolate
- Halogenation
- Alkylation onto a-Carbon of ketones and aldehydes
1.LDA (or NaH)
2.RX
2)
1) LDA
Br
Transcribed Image Text:Ch22. Carbonyl Alpha-Substitution Reactions - Keto-enol Tautomerism Carbonyl compounds react with base to create enolate - Halogenation - Alkylation onto a-Carbon of ketones and aldehydes 1.LDA (or NaH) 2.RX 2) 1) LDA Br
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