Rank the compounds in each group in order of increasing reactivity in nucleophilic acyl substitution. a. CsHsCOOCH3, C3H5COCI, CGH;CONH2 b. CH;CH;COOH, (CH;CH2CO)20, CH;CH¿CONHCH,
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- Complete the following reactions by filling in any missing reactants, reagents or products. a) Zn(Hg) conc. HCl b) ОН ? с) ОН РСС CH,Cl,Draw the organic product(s) formed when CH3CH2CH2OH is treated with each reagent. a.H2SO4 b.NaH c.HCl + ZnCl2 d.HBr e.SOCl2, pyridine f.PBr3 g.TsCl, pyridine h. [1] NaH; [2] CH3CH2Br [1] i.TsCl, pyridine; [2] NaSH j.POCl3, pyridineDraw the structure of the organic product or products formed in the reaction. H₂C HU IN. H HU of H₂ MgBr 1. H₂C A -CH₂ 2. H3O+ Select Draw / || III Rings C H More
- Does the equilibrium favor the reactants or products in each substitution reaction? a. CH;CH2-NH2 Br CH;CH2-Br + "NH2 b. "CN CN + I-a) Propose the products of the following reactions of Lactone P. T 1. LIAIH,, ether 2. Н.О 1. DIBAL S NaOH H;O* 2. H;O* Lactone (P) 2 CH,MgBr4. What are the products obtained from the following elimination reaction? Indicate the major product. CH;CH2CCH3 H2O CI 5. a) Determine the major product that is formed when the alkyl halide reacts with a hydroxide ion in an elimination reaction. CH;CH,CH,CH,CCH3 Br b) For the major elimination product obtained in 5a), which stereoisomer (cis or trans) is obtained in greater yield? Draw the two isomers and provide the names of the compounds.
- Determine which reactions would occur (substitution, elimination, both, or neither). CH;CH,OH a. SN1 O b. E1 C. SN1 & E1 O d. SN2 е. Е2 O f. SN2 & E2 g. No reaction3. Draw the organic products formed in the following reactions. 요 i. S + b. ao [1] LDA 21 CHỊCH, CHO [3] H₂O HCO₂Et [1] NaOEI, EtOH [2] H₂O* CHO NaOEt EIOH -OH, H₂O5. Give the IUPAC name of the following carboxylic compounds. а. СН,CH,С3ССООН b. CH;CH(NH;)CH(OH)COOH c. (CH;)C=CHCOOH d. CH3 СООН е. NO, COOH O,N 'NO2
- Br H3CO LOCH3 A MgBr 1. CH3OH (2 equiv), H+ 2. Mg 3. 4. H30+ H3COOCH3 в ОН major organic product? НО. OH C OH D ОНWhat is the major organic product obtained from the following reaction sequence? OCH CH 1. NaOCH,CH, CH3CH,OH 2. OCH;CH, 3. Н,о" O 4 O 1 O 3Draw the organic products formed when cyclopentene is treated with each reagent. With some reagents, no reaction occurs. a.H2 + Pd-C b.H2 + Lindlar catalyst c.Na, NH3 d.CH3CO3H e.[1] CH3CO3H; [2] H2O, HO− f.[1]OsO4 + NMO; [2] NaHSO3, H2O g.KMnO4, H2O, HO− h.[1] LiAlH4; [2] H2O i. [1] O3; [2] CH3SCH3 j.(CH3)3COOH, Ti[OCH(CH3)2]4, (−)-DET k.mCPBA l.Product in (k); then [1] LiAlH4; [2] H2O