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Briefly discuss how we can improve pharmacodynamic properties of H1-Antihistamine drugs?
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- how we can improve pharmacokinetic factors( distribution) for the development of H1-Antihistamine drugs?How we can establish or improve Structure activity relationship(SAR) for the development of H1-Antihistamine drug?What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?
- How does physicochemical properties of a drug define its biological mechanism? Please explain at your own words.What are Targeted drug delivery systems ? Please explain the ideal properties of Targeted drug delivery systems?What properties of drug are relevant for developing modified release drug delivery formulation. Please briefly explain this at your own words.