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Q: What is more preferred for drug therapy, conventional or modified release dosage forms?
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Q: drug therapy, conventional or modified release dosage forms
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Q: Write the Drug Discovery Process of Diltiazem?
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Q: What is the mechanism of action of the drug LIDOCAINE? pls. dont plagiarize
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What properties of drug are relevant for developing modified release drug delivery formulation. Please briefly explain this at your own words.
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- Please give me a discussion/explanation of ( TARGET SELECTION ) part in drug discovery and development.What are the different methods for developing modified release drug delivery system ? Discuss about the matrix and encapsulation drug release systems. Please explain at your own words.Biotransformation is an important concept in pharmacology, which amongst others, enables the effective administration of prodrugs. Provide a detailed description of factors influencing the biotransformation of drugs.
- What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product? This under Bipharmaceurics and Pharmacokinetics subjectPlease Write the Drug Discovery Process of Diltiazem? Please write at your own words.What is the mechanism of action of the drug LIDOCAINE? pls. dont plagiarize
- Write about Pfizer-BioNTech COVID-19 vaccine (Tozinameran) You must include the following information Chemistry of the drugs: Structure, physicochemical properties, (log P, pKa, & stereochemistry) and chemical properties and stability. Mechanism of action: (including the possible drug target interactions) in CoVid-19 Pharmacokinetic: Absorption, distribution (% plasma binding), chemical basis of metabolic pathways and elimination Pharmacological properties including side effect, ADR, drug interaction, precautions, dose and dosage forms Stability and storage conditions, as well as Brand namesDrug development follows a structured sequence of different steps ensuring safety and aiming at therapeutic progress = The process is structured by the successive conduct of -phase I, II, and III clinical trials using your power point write briefly about these phases showing as an example the .time line for Pfizer corona vaccineWhat is more preferred for drug therapy, conventional or modified release dosage forms? Please provide informations that would support the claim.
- Answer the following questions:1. If excipients do not have pharmacodynamic activity, how do excipients affect the performance of the drug product?2. What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product?3. What is the usual rate-limiting step for a poorly soluble and highly permeable drug (BCS 2)?4. How could the manufacturing process affect drug product performance?5. Drug absorption involves at least three distinct steps: dissolution, permeation, and disposition during transit in GI (an additional step of drug disposition in the body is involved as well for bioavailability). How are these processes validated in vitro when the in vivo requirement for drug bioavailability is waived?6. What is meant by “sink” conditions?7. What physical or chemical properties of a drug substance are important in designing a drug for (a) oral administration or (b) parenteral administration?8. For a lipid-soluble drug that has very poor aqueous solubility, what…Please briefly explain How preformulation studies help to find the drug performance and the development of a dosage form-Briefly explain this with different drug properties and example? Please briefly answer at your own easy words.Discuss three types of drug-drug interactions, and explain the links to pharmacodynamics and/or pharmacokinetics, with examples. Give the mechanims.