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- Use the scoring system described to calculate the alignment score for IPNI AAIG DV VAGP VKGIYA VG DV C-GK Scoring system: • Each identity results in +10 points. • Each gap has a penalty of -25 points. score = What is the percent identity (also called percent identity match)? percent identity: %a- What is De Bruijn graph, and why it is used? b- Given the folowing string ACGCGTCG. draw De Bruijn graph where K-3stion 6 of 18 Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver. She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F, females in a testcross. She obtains the flies from this testcross. Phenotype Number of flies vg* qu+ 230 vg qu 224 vg qut vg* qu 97 99 Test the hypothesis that the genes quiver and vestigial assort independently by calculating the chi-squared, X², for this hypothesis. Provide the X2 to one decimal place. X2 = Does the X value support the hypothesis that the quiver and vestigial genes assort independently? Why or why not? the partial table of critical values for X2 calculations to test this hypothesis.
- Possible equations to use: PID,] = 1- (PBa + 3/4 Pab + 1/2Pbb)" !3! log (1-PID,) log (Pa8 + 3/4 P8b+ 1/2Pbb) n = 8. A breeder is concerned that his best purebred Angus bull may be a carrier for Curly Calf Syndrome. He decides to conduct some test matings by taking this bull and mating him to 15 of the bulls own daughters to determine if he is a possible carrier of this and any other undesirable recessive genes. Show your work. a. How sure would we be that he is not a carrier if all the calves are born normal? b. How many would you need to be 99% sure he was not a carrier?Fill the punnet square for just cross 2 and then do the chi square by using the observed values of cross 2 given in the picture:Consider three genes L, U, and W, for which the count of F2 phenotypes after a 3-point cross is as follows: Phenotype F2 count: L U w 19 L u W 1 l u W 21 L U W 33 l U W 274 l u w 41 l U w 2 L u w 259 Which of the following statements about genes L, U, and W are TRUE? (may be more than one correct ans) A. L, U, and W are each on a different chromosome B. Only U and L are on the same chromosome C. Only U and W are on the same chromosome D. Only W and L are on the same chromosome E. L, U, and W are all on the same chromosome
- What is the answer for number 4 and how do you calculate this?Suppose you use the semi-global Needleman-Wunsch algorithm to alignGAGATAGwithGACwhere match = 1, nonmatch = 0, gap = -1 When you do the backtracking, how many optimal paths will be found?In a standard deck of playing cards, four suits exist(red suits = hearts and diamonds, black suits =spades and clubs). Each suit has 13 cards: Ace (A),2, 3, 4, 5, 6, 7, 8, 9, 10, and the face cards Jack (J),Queen (Q), and King (K). In a single draw, what isthe probability that you will draw a face card? A redcard? A red face card?