Based on the attached figure (Figure 9.7 in the textbook), what intracellular signaling mechanism ultimately causes the light- induced hyperpolarization of a photoreceptor? (A) N (C) FRIES Outer segment membrane Opsin 11-cis retinal -Light Rhodopsin GDP Transducin Disk Ell PDE M (B) 11-cis retinal Disk membrane ........... All-trans retinal GMP GMP 12 12 GMP CGMP CGMP CGMP) Nat 11 Light Inside of cell Open channel Closed channel Outside of cell Na+ Ca²+ decrease in cGMP inactivation of a phosphodiesterase activation of guanylyl cyclase increase in cGMP activation of adenylyl cyclase

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 12P
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Question
Based on the attached figure (Figure 9.7 in the textbook), what
intracellular signaling mechanism ultimately causes the light-
induced hyperpolarization of a photoreceptor?
(A)
N
(C)
FRIES
Outer segment
membrane
Opsin
11-cis
retinal
-Light
Rhodopsin
GDP
Transducin
Disk
Ell
PDE
M
(B)
11-cis retinal
Disk
membrane
...........
All-trans retinal
GMP
GMP
12
12
GMP
CGMP
CGMP
CGMP)
Nat
11
Light
Inside
of cell
Open
channel
Closed
channel
Outside
of cell
Na+
Ca²+
Transcribed Image Text:Based on the attached figure (Figure 9.7 in the textbook), what intracellular signaling mechanism ultimately causes the light- induced hyperpolarization of a photoreceptor? (A) N (C) FRIES Outer segment membrane Opsin 11-cis retinal -Light Rhodopsin GDP Transducin Disk Ell PDE M (B) 11-cis retinal Disk membrane ........... All-trans retinal GMP GMP 12 12 GMP CGMP CGMP CGMP) Nat 11 Light Inside of cell Open channel Closed channel Outside of cell Na+ Ca²+
decrease in cGMP
inactivation of a phosphodiesterase
activation of guanylyl cyclase
increase in cGMP
activation of adenylyl cyclase
Transcribed Image Text:decrease in cGMP inactivation of a phosphodiesterase activation of guanylyl cyclase increase in cGMP activation of adenylyl cyclase
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