Animation 12.1: This table shows results from allele specific oligonucleotide hybridization analyses conducted on three different patients. The analyses all used the same probes constructed to test for the presence of a mutant gene. A plus sign (+) indicates hybridization occurred and a negative sign (-) indicates no hybridization occurred. Patient #1 Patient #2 Patient #3 Probe for nomal +] allele Probe for mutant allele Which patient(s) is/are homozygous for the mutation and which patient(s) is/are heterozygous for the mutation? O Patients 2 and #3 are homozygous and Patient #1 is heterozygous for the mutation. O Patient 22 is homozygous and Patient #1 is heterozygous for the mutation. O Patient #1 is homozygous and Patients #2 and #3 are heterozygous for the mutation. O Patient #1 is homozygous and Patient #2 is heterozygous for the mutation.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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3. Animation 12.1: This table shows results from allele-specific oligonucleotide hybridization analyses conducted on three different patients. The analyses all used the same probes constructed to test for the presence of a
mutant gene. A plus sign (+) indicates hybridization occurred and a negative sign (-) indicates no hybridization occurred.
Patient #1
Patient #2
Patient #3
Probe for normal
allele
Probe for mutant
allele
Which patient(s) is/are homozygous for the mutation and which patient(s) is/are heterozygous for the mutation?
O Patients #2 and #3 are homozygous and Patient #1 is heterozygous for the mutation.
O Patient #2 is homozygous and Patient #1 is heterozygous for the mutation.
O Patient #1 is homozygous and Patients #2 and #3 are heterozygous for the mutation.
O Patient # 1 is homozygous and Patient #2 is heterozygous for the mutation.
Transcribed Image Text:3. Animation 12.1: This table shows results from allele-specific oligonucleotide hybridization analyses conducted on three different patients. The analyses all used the same probes constructed to test for the presence of a mutant gene. A plus sign (+) indicates hybridization occurred and a negative sign (-) indicates no hybridization occurred. Patient #1 Patient #2 Patient #3 Probe for normal allele Probe for mutant allele Which patient(s) is/are homozygous for the mutation and which patient(s) is/are heterozygous for the mutation? O Patients #2 and #3 are homozygous and Patient #1 is heterozygous for the mutation. O Patient #2 is homozygous and Patient #1 is heterozygous for the mutation. O Patient #1 is homozygous and Patients #2 and #3 are heterozygous for the mutation. O Patient # 1 is homozygous and Patient #2 is heterozygous for the mutation.
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