7. After visiting a gym, a student had 250-300 g of carbohydrates for lunch and decided to rest. How will the student's metabolism of carbohydrates and fats in the adipose tissue change 2 hours after meal? b) name the hormone that has ILs lever elevated in the student's blood in the absorptive state and describe the hormonal signal transduction to adipose tissue;
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- 8. The adipose tissue is not only store triacylglycerols but also is active endocrine organ. Explain this function of the adipose tissuc. For that: a) explain the «clinical obesity» and possible consequences of the discase; b) name the biologically active molecules secreted by the adipose tissue; c) explain how secretion of these molecules changes with development of obesity. 9. A daily dict ofa 55-ycar-old woman, consisted ofa 500 g of carbohydrates, 100g of animal fats and 150 g of proteins, at the background of low physical activity.3. A patient has got excess carbohydrate meal for the years and gain the weight. To explain this: a) draw the schemes of TAG synthesis in the liver; b) describe the transport of TAG from the liver to adipose tissue; c) describe the functions of insulin in the conversion of glucose to TAG in the liver and adipose tissue. Glucose containing Catoms was added to isolated hepatocytes inanexperiment. Ifthe glucose was added in excess, the rate of triacylglyccrol synthesis increased.3. After 12 days of starvation, a man reduced his weight by 4 kg. The doctor prescribed him biochemical blood test to analyze the level of lipids in serum blood. The results showed an elevated level of free fatty acids and triacylglycerols. Explain the results of the biochemical blood test. For that: a) name the main hormone which manages metabolism during starvation; b) draw the scheme of this hormone action on the adipose tissue; c) name the possible pathways of fatty acids usage in the liver during starvation and write down the proper schemes.
- Discuss the 3 mechanisms of abnormal carbohydrates metabolism that result in the development of ketone bodies in the urine and give examples of the condition to each.1.. Discuss how the inability to synthesize insulin and glucagon would impact lipid and/or carbohydrate metabolism.1A. Produceadiagramtoillustratethedifferenttypesofmoleculesfoundincells.Briefly describe their properties and functions within the cell. In a separate diagram, describe how carbohydrates, amino acids and triacylglycerides interact metabolically in the generation of energy in the form of ATP.B. Mineralsandvitaminsareimportantnutritionalmoleculesbecausetheyfunctionas cofactors for critical enzymes in living systems. Without them, important biochemical reactions required for growth and tissue repair will not occur. Knowing this, explain the biochemical significance of folate and iron supplementation in pregnant women and women of reproductive age. Consider the effects of folate and iron deficiency as well. 2A. Thevalueofenzymesinlivingsystemsisthatwithoutthem,chemicalreactionsrequired for life to exist would not be possible under physiological conditions. On the basis of this, discuss how enzymes make life possible from a biochemical perspective. Include the following terms in your…
- 24. Jenny’s body mass index (BMI) is too high, and she wants to lose some weight. Is there a hormone that can suppress appetite? Explain.8. In patients with diabetes mellitus type I, the biochemical disorders result from changes in fucl metabolism. One of these signs is acidosis. Explain why such patients have a deviation of blood pH from the norm? For this me the Ocuics, name d) specify the hormone that accelerates this preeursor formation and provide appropriate charts, starting from the hormone binding to adipocyte and concluding with precursor formation, give an explanation to the charts.2. How does the fatty acids concentration changes in the blood during prolonged fasting? To answer the question: a) name the hormone which manages metabolism in this condition; b) draw the scheme of this hormone action on the adipose tissue; 352 Chapter 7. Lipid metabolism c) draw the scheme of the main metabolic pathway providing energy for the liver during prolonged fasting.
- 8. In patients with diabetes mellitus type I, the biochemical disorders result from changes in fuel metabolism. One of these signs is acidosis. Explain why such patients have a deviation of blood pH from the norm? For this: d) specify the hormone that accelerates this precursor formation and provide appropriate charts, starting from the hormone binding to adipocyte and concluding with precursor formation, give an explanation to the charts.Using a diagram, summarize the events of the postabsorptive state; include the four sources of blood glucose and the pathways leading to ketone formation.What happens to the triglyceride concentrations in the plasma and in adipose tissue after administration of a drug that blocks the action of lipoprotein lipase? Hint: imagine where lipoprotein lipase acts in that figure.