5. During prolonged fasting, amino acids derived from muscle proteins and connective tissue become the main substrate for gluconcogenesis. How does glutamate enter the gluconcogenesis? For answer: a) write a reaction of the glutamate conversion into a-ketoglutarate, name the enzyme, indicate the energy effect of the reaction; b) draw a diagram for the a-ketoglutarate conversion to oxaloacetate and consequent including of OAA to gluconcogenesis, specify the reactions associated with ATP consumption; c) name the hormones that accelerate gluconcogenesis during fasting and regulatory enzymes of the process; and describe the mechanism of signal transduction by these hormones
5. During prolonged fasting, amino acids derived from muscle proteins and connective tissue become the main substrate for gluconcogenesis. How does glutamate enter the gluconcogenesis? For answer: a) write a reaction of the glutamate conversion into a-ketoglutarate, name the enzyme, indicate the energy effect of the reaction; b) draw a diagram for the a-ketoglutarate conversion to oxaloacetate and consequent including of OAA to gluconcogenesis, specify the reactions associated with ATP consumption; c) name the hormones that accelerate gluconcogenesis during fasting and regulatory enzymes of the process; and describe the mechanism of signal transduction by these hormones
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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