4. Each of the following compounds has a stereocenter, marked by an asterisk (*). For each of the stereocenters: i. Identify the highest priority group. ii. Determine whether the stereocenter is (R) or (S). Remember that the lowest priority group MUST be oriented back. Completely fill in the circle in front of your chosen answer. H3C HO H (a) The highest priority group is: O CH3 O Double bond ΟΗ O OH The stereocenter is: OR OS carbon a OR OS CH3 (b) The highest priority group is: O Carbon a O CH3 O Carbon b ΟΗ The stereocenter is: carbon b (c) The highest priority group is: O CI O CH3 ΟΗ OF F сний C CH3 The stereocenter is: OR OS

4. Each of the following compounds has a stereocenter, marked by an asterisk (*). For each of the stereocenters: i. Identify the highest priority group. ii. Determine whether the stereocenter is (R) or (S). Remember that the lowest priority group MUST be oriented back. Completely fill in the circle in front of your chosen answer. H3C HO H (a) The highest priority group is: O CH3 O Double bond ΟΗ O OH The stereocenter is: OR OS carbon a OR OS CH3 (b) The highest priority group is: O Carbon a O CH3 O Carbon b ΟΗ The stereocenter is: carbon b (c) The highest priority group is: O CI O CH3 ΟΗ OF F сний C CH3 The stereocenter is: OR OS

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter15: Chirality: The Handedness Of Molecules

Section: Chapter Questions

Problem 15.24P

See similar textbooks

Similar questions

4. Find the R and S configuration in the following compounds. H OCH 3 HOCH 2 CO₂H 5. Draw the product of the following reaction? Br OC(CH3)3 6. Find the R and S configuration and name the following compounds. H OH H H3C 7. Draw the product of the following reaction explain if there is any stereochemistry. Br NaOH -HBr
9. Circle each of the stereogenic (chiral) carbons in the following molecule of cortisone, a steroid hormone released by the adrenal gland in response to stress. Circle correct configuration L H₂C OH 10. In the following molecules, label the substituents on the stereogenic (chiral) carbon in order of priority, and then assign R or S configuration: 1 CH Br CH₂CH₂CH3 R or S H₂C OH HE CH₂CH₂ R or S
On the molecule below, highlight all R stereocenters in red and all S stereocenters in blue. If it doesn't contain any stereocenters, check the "No Stereocenters" box under the drawing area. aill CH₂ X Ś
Determine the R/S designation for the indicated atom. If the atom / center is not a stereocenter, choose neither. R 5 N. neither H H OH Mifepristone. aka RU-486. Causes fetal abortion when used in conjuction with mifeprostol R, S, or neither for this carbon atom
9. Assign each of the following stereocenters as either R or S. Circle your answer below. н он Br. H H Me Ror S Ror S Ror S
Define each stereocenter as either (R) or (S). If the molecule does not have a stereocenter select "achiral". A E G H H OH H H3C FOH H3C CH3 H3C Но -CH3 H- -OH Но- -CH3 но- CH3 H3C- ČH3 H OH В F H
8. Two structures of Lipitor (a drug used to lower cholesterol) are shown below. (a) Determine the absolute configuration of each indicated stereocenter. Fill in the correct circle. (b) Determine if the two structures are the same compound or stereoisomers. Fill in the correct circle. (a) НО. Carbon a HO O OH Carbon a: OR OS Carbon b H N Carbon b: R OS of H Carbon c: OR OS OH OH Carbon c F Carbon d: R OS OH Carbon d (b) The two structures are: O the same compound O stereoisomers
Predict the major product of this series of reactions. The squiggly bond simply indicates the stereochemistry is unknown, i.e., wedge or dash. HBr compound I 1. NaH 2. compoundI 3. H2, Lindlar 4. Br2, H20 OH Br А. Br C. OH OH Br Br В. D. OH A.
11. Using a Fisher projection, draw the 2R,3R,4S stereoisomer of the following compound. F. Br 2. HO H. F Br 12. How many E2 products would result from the following reaction. КОН CH;CH,OH Br A) 1 B) 2 C) 3 D) 4 E) none of the above
On the molecule below, highlight all R stereocenters in red and all S stereocenters in blue. If it doesn't conta box under the drawing area. No stereocenters H₂N X
On the molecule below, highlight all R stereocenters in red and all S stereocenters in blue. If it doesn't contain any stereocenters, check the "No Stereocenters" box under the drawing area. H Ś
Streptimidone is an antibiotic whose structure is shown below. Which of the following gives the configuration of streptimidone's enantiomer? О но н NH H. a O. H. H. CH3 H CH3 R, S, E S, R, E R, S, Z S, R, Z