Answered: 22.34. Starting with diethyl malonate…

22.34. Starting with diethyl malonate or ethyl acetoacetate and any other organic compounds with seven or fewer carbon atoms, propose a synthesis for each of the following compounds: a. COOH b. NH₂

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.52P

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Question

22.34. Starting with diethyl malonate or ethyl acetoacetate and any other organic
compounds with seven or fewer carbon atoms, propose a synthesis for each of the
following compounds:
a.
COOH
b.
NH₂

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Step 1: Dialylation of diethyl malonate

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Step 2: Synthesis of compound a

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Step 3: Reaction with ethylacetoacetate

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Step 4: Syntheisof compound c

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