L.CH,M B дет дета НО (CH₂)₂N Compound A (CH₂) N Tamoxifen

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section: Chapter Questions
Problem 23.61P
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17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the structure of compound A in the synthesis of tamoxifen. Page 707 HO (CH3)2N 1. C,H,MgBr 2. H + Compound A (CH3)2N Tamoxifen

17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the Page 707
structure of compound A in the synthesis of tamoxifen
НО
(CH₂)₂N
ge--ge
1.CH,MgBr
2. H,0
Compound A
(CH₂) N
Tamoxifen
Transcribed Image Text:17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the Page 707 structure of compound A in the synthesis of tamoxifen НО (CH₂)₂N ge--ge 1.CH,MgBr 2. H,0 Compound A (CH₂) N Tamoxifen
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