16.30 Propranolol is a drug prescribed to treat cardiac arrhythmia and angina pain and to lower blood pressure. It is chiral, and one enantiomer is responsible for its therapeutic effects. That enantiomer can be synthesized from (S)-glycidol as shown. What is the configuration of the propranolol formed by this sequence? (No rearrangements occur.) A bond of the type į means unspecified stereochemistry. -Br ONa - NHCH(CH3)2 OH OH OH HO (CH),CHNH- 2. HBr (S)-Glycidol Propanolol

16.30 Propranolol is a drug prescribed to treat cardiac arrhythmia and angina pain and to lower blood pressure. It is chiral, and one enantiomer is responsible for its therapeutic effects. That enantiomer can be synthesized from (S)-glycidol as shown. What is the configuration of the propranolol formed by this sequence? (No rearrangements occur.) A bond of the type į means unspecified stereochemistry. -Br ONa - NHCH(CH3)2 OH OH OH HO (CH),CHNH- 2. HBr (S)-Glycidol Propanolol

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter16: Aldehydes And Ketones

Section: Chapter Questions

Problem 16.40P

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