(a)
Interpretation: The
Concept introduction: Gabriel synthesis is a method of preparation of primary
(b)
Interpretation: The alkyl halide needed to prepare the given primary amine by Gabriel synthesis is to be determined.
Concept introduction: Gabriel synthesis is a method of preparation of primary amines. This is a nucleophilic substitution reaction. The phthalimide in presence of base forms the resonance stabilized anion which acts as a nucleophile and attacks the electrophilic carbon of alkyl haides.
(c)
Interpretation: The alkyl halide needed to prepare the given primary amine by Gabriel synthesis is to be determined.
Concept introduction: Gabriel synthesis is a method of preparation of primary amines. This is a nucleophilic substitution reaction. The phthalimide in presence of base forms the resonance stabilized anion which acts as a nucleophile and attacks the electrophilic carbon of alkyl haides.
Want to see the full answer?
Check out a sample textbook solutionChapter 23 Solutions
Organic Chemistry (6th Edition)
- 18. Identify the lactone formed by the following hydroxy carboxylic acid. A. A B. B C. C D. D OH OH & & A) B) C) D)arrow_forwardWhat carbonyl compound and amine or alcohol are needed to prepare each product?arrow_forwardWhich molecule is hydrolyzed most slowly with aqueous NaOH? D. C. В. A.arrow_forward
- What carbonyl compound and diol are needed to prepare each compound? b.arrow_forwardHow would you convert cyclohexanone into each compound using any required inorganic reagents and needed organic compounds? a. b.arrow_forward16.41) Give on IUPAC or common home for each compound. 2 b. in O d. Hon de jha ok C. e- ion ganho-to- 0 y. ho Y 2-ethylbutonoyl chloride methyl benzoate N-ethyl-N-methylpropion amide ethyl formale benzoic propionic anhydride isopropyl 3-ethyl hexanoatearrow_forward
- Electron inductive effect of alkyl groups decreases the acidity in: A. acetic acid B. benzoic acid C. hydrochloric acid D nitric acidarrow_forwardNot all aldehyde give a positve Bendicts test. Which of the follwing aldehydes do? a. d. b. e. c.arrow_forwardWhich amines cannot be prepared by a Gabriel synthesis? Explain your choices. NH2 NH2 NH2 а. b. C. d.arrow_forward
- Answer the following questions about atomoxetine, a drug used to treatattention deficit hyperactivity disorder (ADHD). a.) What amides can be reduced to form atomoxetine?b.) What starting materials can be used to form atomoxetine by reductiveamination? Draw all possible methods.c.) What products are formed by Hofmann elimination of atomoxetine?arrow_forwardthe carbonyl donor or precursor in the following reaction is: a. A b. B c. C d. NaOHarrow_forwardThe order of increasing acidity is Phenol < meta-cyanophenol < ortho-cyanophenol 1.how about para-cyanophenol??does it has higher acidicity than both ortho-cyanophenol and meta cyanophenol or lower?? 2.why does ortho-cyanophenol have higher acidicity than meta cyanophenol?? 3. why doesmeta cyanophenol have higher acidicity than Phenolarrow_forward
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning