Concept explainers
To determine:
The term non disjunction and how it is responsible for the formation of abnormal chromosomal number.
Introduction:
Humans cell contain 46 chromosomes (2n) and these are diploid in nature but at the time of fertilization only 23 (n) chromosomes are received from mother and 23 (n) chromosomes are received from father to form a zygote by the process of meiosis.
Zygote is formed by the transfer of male gamete (sperm) and female gamete (ova). The ova and sperm are haploid (n) and form a diploid zygote (2n). Zygote receives 46 chromosomes. Some humans are born with abnormalities as they receive abnormal chromosomal number in their cell. Abnormal chromosome is formed when chromosome fails to separate during meiosis and is known as non-disjunction.
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