Concept explainers
(a)
To draw and name: The structure of α-keto acid which results from the transamination reaction of α-ketoglutarate with aspartate.
Introduction:
The α-amino acid is transferred to the a-carbon atom of α-ketoglutarate and leaves behind the corresponding α-keto acid is known as transamination reaction. This transfer of amino group is through the enzymes known as transferases or transaminases.
(a)
Answer to Problem 1P
Correct answer: Fig.1: Structure of oxaloacetate.
Fig.1: Structure of oxaloacetate.
Explanation of Solution
Explanation:
The structure of α-keto acid which results from the reaction of amino acids with α-ketoglutarate is as follow:
The final product obtained from the reaction is oxaloacetate.
(b)
To draw and name: The structure of α-keto acid which results from the transamination reaction of α-ketoglutarate with glutamate.
Introduction:
The α-amino acid is transferred to the a-carbon atom of α-ketoglutarate and leaves behind the corresponding α-keto acidis known as transamination reaction. This transfer of amino group is through the enzymes known as transferases or transaminases.
(b)
Answer to Problem 1P
Correct answer: Fig.1: Structure of α-ketoglutarate.
Fig.1: Structure of α-ketoglutarate.
Explanation of Solution
Explanation:
The structure of α-keto acid which results from the reaction of amino acids with α-ketoglutarate is as follow:
The α-ketoglutarate is the final product obtained from the reaction.
(c)
To draw and name: The structure of α-keto acid which results from the transamination reaction of α-ketoglutarate with alanine.
Introduction:
The α-amino acid is transferred to the a-carbon atom of α-ketoglutarate and leaves behind the corresponding α-keto acid is known as transamination reaction. This transfer of amino group is through the enzymes known as transferases or transaminases.
(c)
Answer to Problem 1P
Correct answer: Fig.1: Structure of pyruvate.
Fig.1: Structure of pyruvate.
Explanation of Solution
Explanation:
The structure of α-keto acid which results from the reaction of amino acids with α-ketoglutarate is as follow:
Pyruvate is the final product obtained from the reaction.
(d)
To draw and name: The structure of α-keto acid which results from the transamination reaction of α-ketoglutarate with phenylalnine.
Introduction:
The α-amino acid is transferred to the a-carbon atom of α-ketoglutarate and leaves behind the corresponding α-keto acid is known as transamination reaction. This transfer of amino group is through the enzymes known as transferases or transaminases.
(d)
Answer to Problem 1P
Correct answer: Fig.1: Structure of phenylpyruvate.
Fig.1: Structure of phenylpyruvate.
Explanation of Solution
Explanation:
The structure of α-keto acid which results from the reaction of amino acids with α-ketoglutarate is as follow:
phenylpyruvate is the final product obtained from the reaction.
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Chapter 18 Solutions
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