Match each of the following aspects of DNA with the main structural feature which makes it possible. You may use each match more than once (or not at all). V Proteins can "read" the DNA without separating the two strands. DNA is resistant to hydrolysis. DNA can be repaired. DNA can self-replicate. 1. DNA does not have a 2' hydroxyl. The two strands in the double helix are complementary. 3. DNA is a polymer of nucleotides. 2. 4. B-DNA has a "major groove".
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- All the following statements about DNA are true, EXCEPT: O DNA is a double-helix, consisting of a sugar-phosphate backbone. O DNA is made up on nucleotides, which consist of one sugar, one phosphate, and one base. O DNA consists of 4 bases - adenine, uracil, cytosine, and guanine. The two main functions of DNA are to replicate itself and to create proteins (by providing the template for protein synthesis). O The sugar in DNA is deoxyribose.What property/characteristics can definitely be concluded from the given composition of a DNA? A = 15% C = 52% T= 24% G = 49% The DNA is double stranded The DNA is single stranded The DNA has supercoiled structures The DNA has a high Tm The DNA has a B conformationDNA has unique properties that allow it to accurately retain genetic information, even after multiple rounds of replication. One aspect of DNA that allows it to accurately store genetic information is the base pairing from Chargaff's first rule of the four nucleotide bases. If the A content of a DNA molecule is 18%, what are the percentages of the remaining bases? T = G = C = % % %
- Complete the structure of a DNA molecule. Label each base A, T, G, C. Sugar (s) Phosphate (P) group on the complimentary strand.During the synthesis of a DNA molecule, nucleotides are added sequentially to the growing DNA molecule via bonds between the previously added nucleotide and the next nucleotide. The figure below illustrates a partial strand of a DNA molecule. W, X, Y, and Z denote differ- ent chemical bonds on the DNA strand. 5' end OH 0-P-0 A W B X с o Y 0 3' end The molecular structure of a DNA strand D Z OP 0 0X CH, -0- Which of the four labeled bonds was last to form during DNA synthesis? W CH, OHWhich of the following statements regarding DNA is false? Features a beta glycosidic bond between deoxyribose and nucleobase. Phosphoester bonds in DNA are extremely stable to non-catalytic hydrolysis. In B DNA the parallel stacks of nucleobases are separated by about 3.5 A A DNA is formed from single strands of RNA and DNA DNA contains uridine, adenosine, guanosine, and cytidine as nucleobases.
- Which of the following is true about DNA ? * Two DNA strands are twisted around each other to form an anti-parallel double helix Adenine pairs with thymine though 2 hydrogen bonds (A=T) Guanine pairs with cytosine through 3 hydrogen bonds (GEC). O All of themThe final steps of DNA synthesis involve the removal and replacement of primers with DNA, and the formation of the final phosphodiester bonds of the backbone which join all the fragments into one unbroken strand of DNA. True or false?Match each of the following terms with the one definition that best describes it. Any of the following: Uracil, Cytosine, Thymine, Adenine, Guanine ····· Closes "nicks" between DNA fragments, forming a covalent bond that joins the fragments together Lays down a short chain of nucleotides at the beginning of DNA replication Synthesizes mRNA from a DNA template Unwinds the DNA double helix during DNA replication Adds individual nucleotides to a growing DNA strand during DNA replication 1. RNA Polymerase 2. DNA Polymerase 3. Ligase 4. Primase 5. Helicase 6. Nitrogenous Base
- Which statement most accurately describes the ‘backbone’ of DNA? Group of answer choices The DNA strand is wound up around histone groups which gives the backbone structure to the chromosome The sugar group from a nucleotide is connected to the next sugar group via a phosphate group The hydrogen bonds between nucleotides are quite strong and provide structure to DNA. Adenine and Thymine, and Guanine and Cytosine are linked togetherThe nucleotides are very specific as to which bond together. The four nucleotides are:Adenine (A) Thymine (T)Guanine (G) Cytosine (C)They are written out in this order because Adenine always bonds with Thymine and Cytosine alwaysbonds with Guanine. Draw a line connecting those so you remember.Let’s practice making complementary strands. DNA: T-A-C-T-T-A-C-A-C-G-T-C-A-A-C-G-T-G-C-C-T-T-A-G-C-C-A-T-TDNA: A-T-GGo ahead and write out the complementary strand to the strand above continuing where we left off.Draw the steps of DNA replication. Use the following nucleotide sequence as reference: 5’ C C T A T G C A G T G G C C A T A T T C C A A A G C A T A G C 3’