Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 1, Problem 13P
Why do scientists think that new genes arise by duplication of an original gene and divergence by mutation?
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Why do scientists think that new genes arise byduplication of an original gene and divergence bymutation?
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When the human genome sequence was finally completed, scientists were surprised to discover that the genome contains far fewer genes than expected. How many genes are present in the human genome? Scientists have also found that there are many more different kinds of proteins in the human cells that there are different genes in the genome. How can this be explained?
Chapter 1 Solutions
Genetics: From Genes to Genomes
Ch. 1 - Choose the phrase from the right column that best...Ch. 1 - If one strand of a DNA molecule has the base...Ch. 1 - The size of one copy of the human genome is...Ch. 1 - Indicate whether each of the following words or...Ch. 1 - a. How many different DNA strands composed of 100...Ch. 1 - RNA shares with proteins the ability to fold into...Ch. 1 - The human protein lactate dehydrogenase shown in...Ch. 1 - a. Are the triplets in the genetic code table...Ch. 1 - Why do scientists think that all forms of life on...Ch. 1 - Why would a geneticist study a yeast cell or a...
Ch. 1 - How can a scientist tell if a protein present in...Ch. 1 - Figure 1.6 shows the amino acid sequences of parts...Ch. 1 - Why do scientists think that new genes arise by...Ch. 1 - Explain how the exon/intron structure of genes...Ch. 1 - Mutations in genes that change their pattern of...Ch. 1 - A single zebrafish gene function was inactivated...Ch. 1 - Different mutations in the WDR62 gene that...Ch. 1 - Researchers have successfully used gene therapy to...Ch. 1 - By the time this book is published, it will likely...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors. All BUT ONE of the statements below correctly describes or explains genetic mutations. A) Mutation can disrupt normal cell activity and cause diseases, like cancer. B) Mutations in parents' cells are then passed down to offspring via reproduction. C) Our cells can recognise any potentially mutation-causing damage and repair it before it permanent. D) Mutations can occur as the result of exposure to environmental factors such as smoking, toxins and radiation.arrow_forwardWhat percentage of the DNA in the genome actually corresponds to genes? How much is actually protein-coding exons? What makes up the rest?arrow_forwardOne unexpected result of the sequencing of the human genome was the finding that mutations in a single gene can be responsible for multiple distinct disorders. How do you think mutations in a single gene can have such diverse effects?arrow_forward
- How is paramutation similar to normal gene mutation? How does it differ? Make a list of similarities and differences.arrow_forwardWhat is the advantage of duplication and divergence of genes?arrow_forwardHow many different explanations can you think of for the observation that the rate of mutation varies across the genome? How would you weigh up evidence for these different ideas to decide which ones have the most explanatory power?arrow_forward
- Name three factors that can influence the mutation rates of human genes.arrow_forwardWhat is the name given to the process that can repair DNA damage and generate genetic diversity? Briefly describe the similarities and differences of the two processes.arrow_forwardAre mutations equally likely to occur in all locations in the genome? Why or why not?arrow_forward
- As discussed, the overall rate of mutations in humans is estimated to be about 1 × 10−8 mutations per base pair per generation. How many new mutations would you expect each person to carry, on average, based on this mutation rate? Other studies have estimated that each person carries about 100 new loss-of-function mutations. How does this number compare with your estimate of the number of mutations based on the mutation rate? What might account for any differences?arrow_forwardCan a harmful mutation-causing genetic disease exist from generation to generation without exhibiting the symptoms of the disease? Explain.arrow_forwardA gene has length of 10000 nucleotides, some of them are ancestral (A) and others are mutant letters (M). Every generation 3% of the ancestral letters turn mutate and become M and 1% of the mutant letters revert to the ancestral state. Write a discrete time model for the number of the mutant nucleotides M (Hint: A = 10000 - M). If initially there are 0 mutant letters (all 10000 are ancestral), predict how many there will be in 10 generationsarrow_forward
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