Human Physiology: From Cells to Systems (MindTap Course List)
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Question

Treatment of the protected oligonucleotide with concentrated aqueous ammonia comprises the last
step in solid-phase synthesis of oligonucleotides. Draw a reasonable mechanism for removal of the
benzoyl protecting group from an adenine residue. Remember this is a non-enzymatic mechanism, under
very basic conditions.  

HN Ph N. N तर न NH3, H2O NH2 N N
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Transcribed Image Text:HN Ph N. N तर न NH3, H2O NH2 N N
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