Brain tumors: 6 things you should know An abnormal growth of tissue in the brain or central spine disrupts the proper functioning of the brain, is called a brain tumor. Generally the cells in our body grow, age, die and are replaced by new cells. This cycle is disrupted by the formation of tumors and cancer. In case of a tumor, more cells are added to the mass since the tumor continues to grow but old and damaged cells do not die. Types of brain tumors While some brain tumors are benign, others
another classification of pancreatic tumor help in decision making of management. This classification depends on the possibility of surgical removal of the tumor: in this way, tumors are judged to be "resectable", "borderline resectable" or "unresectable" (American Cancer Society, 2014). AJCC stages I and II defines the disease without spread to large blood vessels or distant organs such as the liver or lungs with possibility of surgical resection of the tumor (Bond-Smith et al., 2012). The AJCC
as a result of cancers cells traveling from the primary site to the distant sites where they colonize and form a secondary tumor. Logic dictates that the circulatory system holds the greatest potential to provide passage for these cells to travel to distant sites. Once these cancer cells have gained access into the circulatory system, they are referred to as circulating tumor cell (CTC).It has been a tough challenge to effectively capture these culprits in the act. Large in part due to the inability
brain tumors are expressed by a collection of neoplasms which are arising from different cells, both from within the brain parenchyma and from systemic tumors that have metastasized and spread to the brain. Throughout history, malignant brain tumors constitute such a small percentage of overall cancer incidence; therefore, little training has been provided for these tumors. Most these tumors are responsible for the majority of deaths from primary brain cancers. To date, "primary brain tumors, whether
Circulating tumor cells (CTCs) Circulating tumor cells (CTCs), represent tumor cells that contain a heterogeneous populace of cells, including apoptotic tumor and viable tumor cells that have shed into the vasculature or lymphatics from a primary or metastatic tumor and are carried around the body in the circulation by undergoing phenotypic changes that are accompanied by a process called as epithelial-mesenchymal transition (EMT) 64-68. Evidence now suggests that the tumors has ability to make their
with a Glioma Brain Tumor. Even three and a half years after his diagnosis, I still don’t really know much about Gliomas, so I have decided to research this topic. Gliomas are primary brain tumors, which mean they start in the brain. They are a fairly common type of brain tumor. These types of tumors originate in the glial cells. Glial cells in the brain surround and support neurons. Because Gliomas often intermix with normal brain tissue, they are called intrinsic brain tumors. Gliomas show up in
utilized for tumor targeting. Anti-epidermal growth factor receptor (EGFR) Affibody protein (e.g., Ac-Cys-ZEGFR:1907, amino acid sequence: Ac-CVDNKFNKEMWAAWEEIRNLPNLNGWQMTAFIASLVDDPSQSANLLAEAKKLNDAQAPK-NH2) is used to target EGFR that is overexpressed in a wide variety of human tumors. Cheng and co-workers used anti-EGFR Affibody protein as tumor-targeting ligand on 64Cu–Au-IO nanoparticles (PET component: 64Cu, MRI component: iron oxide, specific for EGFR) surface.[63] In their work, A431 tumor cells were
Brain Tumors- Most common cancer in childhood and occur in 25% of all childhood cancers. Neoplasms can come from any cell, which means tumors can form in all different areas of the brain. Tumors can be benign or malignant. Clinical manifestations of brain tumors are directed towards the affected area. Most common symptom is a headache and vomiting. Neurological changes, behavioral changes, cranial nerve neuropathy and vital sign disturbances may occur depending on the location of the brain tumor. Diagnosis
Tumors are an area of swelling in a part of the both that does not always create inflammation. These tumors are usually created by an irregular growth of the tissue. There are two individual kinds of tumors, one called malignant, which is cancerous and the other benign, which is noncancerous. There aren’t any environmental factors that can usually cause either one of these tumors. Genetic disease although, can cause certain tumors that can overpower the genes that stop the formation of tumors. A
Circulating tumor cells (CTCs), represent tumor cells that contain a heterogeneous population of cells, including apoptotic tumor and viable tumor cells that have cast off into the circulation or lymphatic vessels from a primary or metastatic tumor and are transported around the body by undergoing phenotypic changes that are accompanied by a process called as epithelial-mesenchymal transition (EMT) [69-73]. Evidence now suggests that the tumors has ability to make their own blood vessels when they