Ribozyme

The major research questions addressed in the presentation consisted of: why to study microbes? , What are the basics of gene expression? , What’s special about riboswitches? The major hypotheses that were explored during the presentation were “S box” represses genes involved in the synthesis of methionine and SAM in response to the high SAM concentration; and the low SAM results in the readthrough of the termination site. Also “How can gene expression be regulated” and under what conditions/processes

1) Describe the structural domains and mechanism of action of ribozymes. How can ribozymes be useful as therapeutic agents? (10 points) RNA molecules that act as enzymes are called ribozymes. They are capable of catalyzing the cleavage of their own RNA or other RNA substrates (Missailidis, 2008). Ribozymes are involved in viroid replication, RNA splicing and protein synthesis. (Clark & Russel, 2005) The structure of ribozymes consist of a catalytic domain and a substrate binding domain. (Ebrahimian

up with the RNA World Hypothesis in the 1960s. They claimed that life later evolved to use DNA and protein due to RNA’s poor instability, causing ribozymes to become increasingly phased out. The evidence that they had was the ribosome turned out to be ribozyme. Their reasoning for the hypothesis is that RNA was not stable enough which caused the ribozyme to become phased

RNA self-replicates by the ribozymes, which provide catalytic reactions on their own nucleotides. Ribozymes can speed up a reaction and the short RNA sequences are eventually connected due to the ribozyme speeding up the reaction. The short sequences of RNA go with the ribozyme. The ribozyme speeds up the entire polymerization of the sequences. The short sequences become one long strand of RNA. The nucleic acid replication evolved by the ribozymes putting together the short sequences of

Cancer is defined as a category of diseases that consist of cells in the human body dividing at an unstoppable rate and result in spreading to surrounding tissue creating tumors. Cancer affects approximately 14 million people and result in 8.2 million deaths as of 2012. However, researches continue to try and develop many kinds of treatments for cancer patients and aim to find a cure for this monstrous disease. Immunotherapy is one of the treatment options that involve the use of chimeric antigen

A. Definition/Comparison Questions Instructions: In your own words, define the pairs of terms given below. Write in complete sentences, stating the differences and relationships between the two terms, and give specific examples where appropriate. A complete answer usually requires four to eight sentences. Each question is worth four marks, for a total of 40 marks. 1. evolution / selection Selection is the process where environmental or genetic influences determine which type of organisms thrive

The rice genome carries at least two active GA20ox genes namely GA20ox1 and GA20ox2. It was found that GA20ox2 was located on the long arm of chromosome 1, tightly linked to the sd1 locus whereas GA20ox1 does not correspond to the sd1 locus as it is mapped on chromosome 3 of rice genome (Matsuoka et al., 2002). As in figure 2.5, sd1 corresponds to GA20ox2 gene consisting of three exons and two introns. It is strongly expressed in the leaf blade, stem and unopened flower, whereas GA20ox1 is predominantly

a protein called Ribonucleoprotein. If the majority of protein content is eliminated, protein synthesis could be maintained. Therefore, RNA is the most crucial part of the macromolecule and this observation is in agreement with the knowledge of ribozymes, RNA with an autocatalytic capacity. Taken together, it strongly suggests that RNA has a

"off" so that protein cannot be produced. Gene-silencing can target a gene's DNA directly, or target mRNA transcripts made from the gene. There are three types of gene silencing; triple-helix-forming oglionucleotide therapy, RNA interferance and ribozyme therapy. Triple-helix-forming oligonucleotide therapy targets the DNA sequence of a mutated gene to prevent its transcription. This technique delivers short, single-stranded pieces of DNA, called oligonucleotides, that bind in the groove between

Science is so amazing! I mean there are different branches and laws of science like Force x Mass= Acceleration and the Laws of Gravity. There are also so many different theories/hypotheses like Einstein’s Theory of Relativity and the Theory of Evolution. It just fascinates me. In this paper I will discuss six theories/ hypotheses: the Primordial Hypothesis: states that life began in a body of water as a result of the mix of chemicals from the atmosphere and some form of energy.The Iron-Sulfur World