Review of Literature REVIEW OF LITERATURE Classification of antifungal drugs: Barar (2000) reported that, the antifungal drugs may be classified as: 1- Antifungal antibiotics: • Griseofulvin. • Polyenes (Nystatin,Natamycin,Hamycin and Amphotericin B). 2-Synthetic antifungal agents: • Flucytosine,Cotrimoxazole,Dapsone,Haloprogin,Imidazoles, Clotrimazole, Miconazole, Econazole, Ketoconazole, Isoconazole, Sulconazole and Tioconazole. • Triazoles: Fluconazole and Itraconazole. 3-Miscellaneous
Response: Anidulafungin is a semi-synthetic echinocandin with antifungal activity. This agent is selective for fungal cells as it inhibits glucan sythase enzyme and therefore inhibits the synthesis of 1, 3 beta D glucan which is essential for the fungal cell wall. According to Micromedix anidulafungin is approved for adults and pediatrics older than 16 years to treat candida related infections. Anidulafungin is administered as a continuous IV infusion and has good efficacy against Candida
Looking for a cure for nail fungus? You can use home remedies for fungus, buy a product over the counter at the Chemist. Or go to your Doctor for a prescription antifungal medication. There are so many remedies out there it is a matter of finding the one that works for you. It is usually common for people to get nail fungus in their big toes. However, I got it first in the fingernail of my middle finger. Which to this day has never looked the same? It can spread very easily, and the worst part
strokes and diabetes. Statins can also attract stem cells towards damaged tissues, so the stem cells then appear to regenerate the tissue. Griseofulvin is used in both animals and humans to treat fungal infections of the skin, hair and nails (dermatophytes) ; such as Ringworm and nail fungus; it was discovered in 1939 from the mold Penicillium patulum, Griseofulvin is listed on the World Health Organisation's List of Essential Medicines. Administered
1. Describe the mode of actions of the drugs that interfere with protein synthesis. Drugs that interfere with protein synthesis are derived from various actinomycetes species Streptomyces and Micromonospora. They inhibit protein synthesis by binding to one of the ribosomal subunits. Thus, disrupting protein synthesis as the ribosomes can no longer produce proteins. 2. Name and describe the actions of the aminoglycoside subgroup. Aminoglycosides are composed of one or more amino sugars and an
Fungal scalp infections What are fungal scalp infections? Tinea capitis and seborrheic dermatitis (dandruff) are scalp disorders characterized by scaling and itchiness related to fungal infection. Tinea capitis usually affects children and is spread by direct contact. The skin lesions appear as scaly patches on the scalp that are often associated with hair loss (alopecia). Lymph nodes in the head or neck may enlarge as a reaction to scalp infection, but usually resolve with clearance of infection
Onychomadesis Onychomadesis is the separation of the nail plate from the nail bed. It can often look like a more severe case of Beau’s Lines, and leaves the nails with a dull appearance. They will also have white streaks down the length of them and feel very brittle. There is no discomfort, pain, or swelling with this disease. A diagnosis is made through examination of the nail plate. The difference between onychomadesis and Beau’s Line’s is that there is a complete stoppage of nail production
Pharmacokinetics is term related to the ending of a substance that administered in a living organism. It consists of four phases and these are absorption, distribution, metabolism, and renal elimination, which referred to as ADME. There are two classes for pharmacokinetics: linear pharmacokinetics and non-linear pharmacokinetics. Linear pharmacokinetics of drug is a term refer to dose independent and concentration independent pharmacokinetics, in which pharmacokinetic parameters are constant when
Ringworm, dermatophytosis, is a common skin infection. Though titled ringworm, it is a fungus beneath the skin rather than a parasite; It is not a parasite nor a worm. The fungus’ name is derived from its appearance; a circular, red rash shaped as a ring. It is able to survive on skin, nearly all surfaces, and fabric. It is transmitted through contact with contaminated surfaces and body fluids. Symptoms in animals may include patchy areas of hair loss; red, circular lesions beneath the skin, as
The Fundamentals of Spotting, Handling, and Stopping Fungal Toenail Contaminations You can generally spot a toe-nail fungus infection by a variation in the nail's tint. The toenail can turn out to be yellow, white, green, tan, or black. At times, the staining will be restricted to a minor mess on the nail. Moreover, other times it will shelter the entire nail's exterior. At times, the fungus will look like a crumbly material that you can remove and at other times, it will produce on the base of