Donepezil hydrochloride is the active ingredient in the prescription drug Aricept, a common drug used to treat mild, moderate, and severe Alzheimer’s disease and other forms of dementia. It is a reversible inhibitor of the enzyme acetylcholinesterase, which is responsible for the breakdown of the neurotransmitter acetylcholine. Increased levels of acetylcholine are believed to relieve the effects of Alzheimer’s disease. Donepezil hydrochloride is known chemically by the IUPAC name 2,3-dihydro-5,
Alzheimer's disease is a very progressive disease it destroys memory and other important mental activities. It’s a type of disease that causes many problems with memory, thinking and behavior. It gets worse over time and continues to progress for the rest of a person's life. It is important to recognize the symptoms of Alzheimer's. The connection between brain cells and the brain cells themselves generate and die causing a steady loss in memory and mental function. African Americans in the United
You may know someone with a mental health disorders it may be a family members, friends or someone you have come across going to a store, school or work and etc. There are different kinds of mental health's disorders and the three I will be speaking about are Alzheimer’s disease, Insomnia disorder and Sleepwalking disorder. First, I will describe Alzheimer's disease it is a progressive condition that damages areas of the brain involved in memory, intelligence, judgment, language and behavior. According
Donepezil: Fighting memory loss diseases with remarkable positive results. Alzheimer's disease treatment, treatment for Parkinson's disease, Aricept, Donepezil. Introduction: Donepezil is a significant drug marketed under the brand name of Aricept and is manufactured by Eisai and Pfizer. It is approved by United States Food and drug administration and has been marked safe for patients of Alzheimer’s disease treatment as well as treatment of Parkinson’s disease. It considerably slows down the pace
role of Donepezil in the treatment of dementia? Background: A 98-year-old female was recently prescribed a 5 mg daily dose of Donepezil for her memory loss. She wonders how Donepezil will help her recollection. She has not had problems with her memory in the past but has been having trouble remembering names and is easily frustrated by it. Along with dementia, she is also diagnosed with osteoarthritis and has a history of breast cancer. She has no food or drug allergies. Response: Donepezil is a
604301973 Pharmacotherapy Treatment of Alzheimer’s: Donepezil A disease that sweeps across the nation and affects nearly 80% of the population ages 60 and up is known as Alzheimer’s. A misconception that many people believe about Alzheimer’s is that it is a part of getting older. It is not true. Alzheimer’s is an intricate neurodegenerative disorder associated with “protein misfolding and aggregation, oxidative stress, mitochondrial abnormalities and neuroinflammatory process at a molecular level”
Name: Ming Gao NEU ID: 001983161 Donepezil and other acetylcholinesterase inhibitors in Alzheimer’s disease Abstract: Alzheimer’s disease (AD), discovered by Dr. Alois Alzheimer in 1907, is the most common form of dementia. The early symptom of Alzheimer’s disease is having difficulty in remembering recent events. At the advanced stage, the signs and symptoms of AD include: memory loss, confusion, trouble
an increase to 3 mg orally twice daily in two weeks, (b) donepezil 5 mg orally at bedtime, or (c) galantamine 4 mg orally twice daily. All of the medications are cholinesterase inhibitors and are considered first-line pharmacotherapy for AD (Yiannopoulou & Papageorgiou, 2012). In randomized controlled trials, rivastigmine, donepezil, and galantamine showed no significant difference in efficacy (Yiannopoulou & Papageorgiou, 2012). Donepezil was selected. Once-daily dosing has been shown to have
This drug is approved to treat majority of the symptoms for all stages of Alzheimer's. The brand names of Donepezil are Aricept and Aricept ODT. This drug is classified as Cholinesterase Inhibitors, which also include Tacrine also known as Cognex. Donepezil is usually taken in dosage forms of tablets that should be taken orally. The strengths for this prescription are usually 5 mg,10 mg, or 23 mg. The 5 mg, is often white colored
MRI-based volumetric technique, hippocampal atrophy in individuals with AD was studied and compared to individuals with AD under the donepezil treatment. The findings were supportive of donepezil treatment having a slowing effect on the progression of hippocampal atrophy in patients with AD. In fact, the mean annual rate of hippocampal volume loss among the patients on donepezil was 3.82%, which proved to be significantly smaller than the control patients, who had a mean volume loss of approximately 5.04%