CAMPBELL BIOLOGY,VOL.II >CUSTOM<
17th Edition
ISBN: 9781323803677
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question
Chapter 43, Problem 11TYU
Summary Introduction
To explain: The feasibility of treating septic shock with a drug that blocks TLR signaling.
Introduction: The defense system of the organism depends on the effectiveness of their immune system. Organisms have acquired many mechanisms of defense system that protects from pathogens. The innate immune response of invertebrates is specific for a particular group of pathogens. Once bound to receptor of a pathogen molecule, recognition protein initiates the immune response that kills the specific pathogens.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Immune systems of animals are very complex. For an animal's immune system to work properly, certain cells must be able to recognize other specific types of cells, so that they can bind to and communicate with them. These types of interactions allow an immune system to decide if and when to launch an immune response.
For example, dendritic cells must be able to recognize and interact with T-cells, but they do not need to recognize adipocyte cells. Which of the following describes a difference between T-cells and adipocyte cells that would allow dendritic cells to recognize one, but not the other?
A. Adipocyte cells must have a cell wall, while T-cells lack one.
B. T-cells and adipocyte cells must have different types of lipids that compose their plasma membranes.
C. Adipocyte cells must lack endoplasmic reticulum, while T-cells possess endoplasmic reticulum.
D. T-cells and adipocyte cells must have some differences in the carbohydrates and/or…
Inhibitory receptors on lymphocytes down-regulate immune responses by recruiting protein or lipid phosphatases.BCR signaling on B cells is initiated by antigen binding, leading to mTOR activation. This occurs, for instance, when the antigen is a live microbe that binds to the BCR on the B cells. Which one of the forms of antigen shown below the graph would correctly account for the data shown in the figure?
To put an end to the COVID-19 pandemic, vaccines were developed against the virus and people eligible to receive these are encouraged to get vaccinated. How do these vaccines work? *
The vaccine will not cause the disease, but will help develop the body’s first line of defense.
The vaccine mimics the virus that causes the disease and triggers the creation of antibodies.
No answer
The presence of the virus in the vaccine will improve the innate immune response of the body.
The vaccine causes a mild infection that will trigger the production of antibodies against the virus.
Chapter 43 Solutions
CAMPBELL BIOLOGY,VOL.II >CUSTOM<
Ch. 43.1 - Pus is both a sign of infection and an indicator...Ch. 43.1 - MAKE CONNECTIONS How do the molecules that...Ch. 43.1 - Prob. 3CCCh. 43.2 - Prob. 1CCCh. 43.2 - Prob. 2CCCh. 43.2 - WHAT IF? If both copies of a light-chain gene and...Ch. 43.3 - Prob. 1CCCh. 43.3 - Treatment of antibodies with a particular protease...Ch. 43.3 - Prob. 3CCCh. 43.4 - Prob. 1CC
Ch. 43.4 - Prob. 2CCCh. 43.4 - WHAT IF? How would a macrophage deficiency likely...Ch. 43 - In what ways does innate immunity protect the...Ch. 43 - Why is the adaptive immune response to an initial...Ch. 43 - Is immunological memory after a natural infection...Ch. 43 - Prob. 43.4CRCh. 43 - Prob. 1TYUCh. 43 - An epitope associates with which part of an...Ch. 43 - Prob. 3TYUCh. 43 - Level 2: Application/Analysis 4. Which of the...Ch. 43 - Prob. 5TYUCh. 43 - Prob. 6TYUCh. 43 - Prob. 7TYUCh. 43 - Prob. 8TYUCh. 43 - MAKE CONNECTIONS Contrast clonal selection with...Ch. 43 - EVOLUTION CONNECTION Describe one invertebrate...Ch. 43 - Prob. 11TYUCh. 43 - Prob. 12TYUCh. 43 - SYNTHESIZE YOUR KNOWLEDGE This photo shows a child...
Knowledge Booster
Similar questions
- Bacteriophage is added to a culture of human T cells and none of the human T cells were infected by bacteriophage. Why? T cells do not have the proper protein machinery to carry out transcription and translation of bacteriophage genes. T cells do not have the corresponding cell surface receptors that are recognized by bacteriophage viruses. T cells have a thick outer cell wall that blocks bacteriophage infection. T cells do not carry out DNA replication and thus are not good hosts for the bacteriophage viruses.arrow_forwardBased on these data, where would you MOST likely find toll-like receptor-XX (TLR-XX) among the following options? Justify WHY you selected that option.Your justification must be based on the data that are presented here, not the type of bacteria. A. On the cell surface B. In the endosome/ lysosome C. In the nucleus D. In the mitochondria E. In the endoplasmic reticulumarrow_forwardHypothetically, HPV was used to cure cancer where the cancer was recognized to be foreign by our host immune response. So therefore, which of the following best illustrates how HPV was used to cure cancer?a. The HPV induced a type IV hypersensitivity immune responseb. The HPV induced a type III hypersensitivity immune responsec. The HPV induced a type II hypersensitivity immune responsed. The HPV induced a type I hypersensitivity immune responsee. The HPV induced a type IV autoimmune responsearrow_forward
- You are studying SARS-COV2. You identify a viral protein that results in the decrease of MHC class I, a cell surface receptor, on the cell surface. You are trying to determine the mechanism for how the virus is decreasing cell surface MHC I. You decide to do an experiment to determine whether the receptor is making it all of the way through the secretory pathway. You take two samples of cells. 1. Uninfected 2. Infected with SARS-CoV2 You treat them with EndoH and analyze MHC I on a western blot and get the following results: 1. Uninfected cells - 50% of protein is endo H sensitive and 50% is Endo H resistant 2. SARS-COV2 infected cells - 100% of protein is Endo H sensitive How would you best interpret these results? Is MHC I going all the way through the secretory pathway in infected cells? A. No, MHC I is not going all the way through the secretory pathway. 100% of the protein is EndoH sensitive in infected cells, this means that the virus is somehow inhibiting the protein from making…arrow_forwardWould it be effective to use an inhibitor of RNA polymerase to block the HIV replication cycle and subsequent infection of human T cells? Yes, this would stop the transcription of viral genes and prevent HIV from being able to replicate. No, these types of inhibitors do not exist and would be impossible to make. No, this would block transcription of T cell genes, leading to the death of T cells and compromised immune systems in individuals. Yes, inhibitors of RNA polymerase are easy and relatively inexpensive to produce and make good therapeutics.arrow_forwardIndividuals or mice with defects in the biochemical pathways needed for loading peptides onto MHC molecules show greatly increased susceptibility to virus infections. Experiments examining the MHC molecules present on the surface of host cells in these individuals would show: Normal numbers of MHC molecules expressed on host cells, but no peptides bound to them. Very low levels of total MHC proteins expressed on the cell surface. Normal numbers of MHC proteins on the surface but all of them bound to self-peptides not pathogen peptides. Very high levels of total MHC proteins expressed on the cell surface. Only virus-infected cells expressing high levels of MHC proteins on the cell surface.arrow_forward
- The small fragments of some complement proteins initiate a local inflammatory response. Recent studies using mouse models of pulmonary inflammation (a model for human asthma) have found that mice deficient in the C3a receptor have greatly reduced disease symptoms when challenged with inhaled preparations containing extracts of the fungal pathogen Aspergillus fumigatus. Specifically, the C3a receptor-deficient mice showed reduced influx of granulocytes and lymphocytes into the lung and reduced fluid in the lung after challenge. What is the explanation for these findings?arrow_forwardWould you predict that TLR-XX is able to recognize other types of Gram-negative bacteria, in addition to the one that was used in this experiment? Explain WHY or WHY NOT?see attached diagram.arrow_forwardHuman immune system a) Pathogen-associated molecular patterns are conserved molecular structures produced by microorganisms, but not by host cells. b) A virus-infected host cell that displays a viral antigen via MHC class I molecules may become a target of cytotoxic T cells. c) Secreted MHC Class I proteins present in blood plasma can function as opsonins. d) Both (a) and (b) are correct and (c) is incorrect e) Statements (a), (b) and (c) are all correctarrow_forward
- Explain the mechanism of the Cancer therapy by inhibition of negative immune regulation, don’t forget to mention about Cytotoxic T Lymphocyte Antigen 4 Mechanism and Programmed cell death protein 1 Mechanism and the receptors. Please all details needed all the proteins everything needs to be in the answer. and i need a long answer not just two words for each. I will rate. If you can use tables it would be great if no it’s okay. I will rate. No hand-written.arrow_forwardPoliovirus is highly cytopathic both in cultured cells and in animals. Inoculation of mice with poliovirus leads to a robust antibody and cellular response. Explain why mice infected with a poliovirus mutant that cannot cause cell death have poor antibody and cellular responses. What would be one strategy to restore robust antibody and cellular responses in mice infected with this mutant virus?arrow_forwardYou can choose one or more than one option Antibodies: IMMUNOLOGY basic have two identical antigen-binding sites. consist of two identical heavy chains and two identical light chains. are secreted by plasma cells are produced by T lymphocytes during adaptive immune response can bind their constant heavy chain region to phagocytes Which of the following proteins are transmembrane proteins? CELL BIOLOGY basic integrin oestrogen receptor phospholipase C adenosine triphosphate (ATP) synthase growth factor receptor What are the correct statements? MOLECULAR BIOLOGY advanced A mutation located within a promoter can change the gene expression. An mRNA can be differentially spliced according to the tissue. RNA transcribed by the RNA polymerase II are translated The end of the transcription process requires a specific DNA sequence A reverse transcriptase can polymerise either a DNA or an RNA strand. Which of the following cells kill other cells by exocytosis of…arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning