Chapter 3.2, Problem 33E

what would the overall reaction be for the recrystillzation of aspirin using 91% isopropanol to get pure aspirin?(drawn out) what would the mechanism be(if any)?   More information provided below:   You are removing salt, talc and other impurities to get pure aspirin. Recrystallization is a useful technique that can be used to purify solid organic compounds. Thistechnique involves the solubility of organic solids in various solvents. For recrystallization towork properly, the target compound must dissolve in a solvent when it is hot and not dissolvewhen it is cold. In this experiment you will isolate pure aspirin from aspirin tablets. Aspirin tabletscontain various salts and impurities in addition to aspirin. By using recrystallization, you will beable to remove the impurities and be left with pure aspirin.Sometimes pairs of solvents can used to produce better results. In this experiment, 91%isopropanol will be used to recrystallize aspirin. The 91% isopropanol contains 91%…

Upon completing a synthesis, you attempt to purify your material via recrystallization. You dissolve the material in a minimal amount of hot solvent and then immediately place the vessel in an ice bath. You obtain the solid product through vacuum filtration. Any issues here? No issues, this is what you would do! You may have an impure solid due to rapid cooling of the vessel. You should have started with RT solvent to dissolve the material. You should use gravity filtration for the final isolation.

Product Separation Scheme Draw a separation scheme to summarize how the pure product can be isolated; Begin by listing all the compounds that could be mixed in with your product, i.e. all reactants, solvents, and other products; in each separation step include the solvent(s)/reagent and separation technique, phases/states of matter for each separation.

You are employed as a coop student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated, and the residue will be tested for the drug.You find that methylphenidate is highly soluble in 2-methyltetrahydrofuran, a bio-renewable solvent. Draw the structure of 2-methyltetrahydrofuran and give two reasons why it is a good solvent choice for liquid-liquid extraction.

For either of these solvents explain why it would be a better choice as a recrystallization solvent than the other (water vs. ethanol).

An organic chemistry laboratory Extraction; the extraction of crude naphtalene- benzoic acid mixture. Naphthalene is a suspect carcinogen and is toxic to aquatic life. Find an alternative pair of molecules that adhere better to the principles of green chemistry and can be separated by extraction using green' solvents. (kindly answer fully)

Diethyl ether and methylene chloride are generally not suitable for use in recrystallization, but are frequently used as extraction solvents. Explain

You are employed as a coop student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated, and the residue will be tested for the drug.Your colleague is helping you develop the urine test. They suggest that the urine should be adjusted to a pH above 7 before extracting with the organic solvent. Why is this necessary? Support your explanation with a full arrow-pushing mechanism for the reaction that would occur if the pH was below 7. Include all formal charges, intermediates (if applicable) and products.

You wash a separatory funnel with soap and water to ensure it is clean before extracting an aqueous solution with dicholormethane. You should take the time to make sure there are no drops of water left inside the separatory funnel. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a True False