Concept explainers
The tiny frog paedophryne amauensis was discovered by researchers purposefully searching for the source of an unusual sound, but sometimes similarity between two species can lead scientists to accidental discoveries. A previously unknown species of wild cat was inadvertently discovered by researchers who were sequencing the DNA of a house cat-sized South American wild cat called the tigrina. The DNA analysis revealed that many alleles found in the supposed tigrinas living in northeastern Brazil are not shared with other tigrinas. This finding suggested that the northeastern cats do not interbreed with other tigrinas and are therefore a different species. What prevents the two species from interbreeding?
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Biology: Life on Earth with Physiology (11th Edition)
- Steven Frank and Laurence Hurst argued that a cytoplasmically inherited mutation in humans that has severe effects in males but no effect in females will not be eliminated from a population by natural selection because only females pass on mtDNA (S. A. Frank and L. D. Hurst. 1996. Nature 383:224). Using this argument, explain why males with Leber hereditary optic neuropathy are more severely affected than females.arrow_forwardYou are studying two populations of pika. You find that the population inhabit in talus (broken rocks) are greyish. Another population live in coniferous forests have black fur. When individuals from each population are brought together in the lab, they produce offspring whose appearance is intermediate between the two parents. The offspring can breed and reproduce successfully with each other or pika of either parent population. You sequence three genes, Pigmentosa, Sparkly, and Zippy. For each of the three genes, the two populations differ from each other at a few nucleotides (<1%). Why is it hard to determine if these two pika populations belong to the same species or are two different species? In your answer/argument, refer to at least two pieces of evidence from the above scenario. Note, we are NOT asking you to determine if these are the same species or not.arrow_forwardBlue eye color allele (b) is recessive to the dominant to the black eye color allele (B). When we sequence around the locus of the blue gene from 10 pure breed species and 10 black pure breed species we notice difference in dna sequence. The black eye species have short tandem repeat (STR), which is a short DNA sequence that is repeated 6 times in the species with blue eyes, and 10 times in the species with black eyes. These repeats are only 4 cM apart from the orange gene locus. You design a PC test that distinguishes between the 6 and 10 STRs by electrophoresis. Make pedigree that will let us to identify which alleles of the blue gene was the dominant and or recessive?arrow_forward
- A total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1arrow_forwardIn a study of a muscle disorder, several affected families exhibited vision problems, muscle weakness, and deafness (M. Zeviani et al. 1990. American Journal of Human Genetics 47:904–914). Analysis of the mtDNA from affected members of these families revealed that large numbers of their mtDNA molecules possessed deletions of varying lengths. Different members of the same family and even different mitochondria from the same person possessed deletions of different sizes, so the underlying defect appeared to be a tendency for the mtDNA of affected persons to have deletions. A pedigree of one of the families studied is shown below. The researchers concluded that this disorder is inherited as an autosomal dominant trait, and they mapped the diseasecausing gene to a position on chromosome 10 in the nucleus. Q. What characteristics of the pedigree rule out inheritance of a trait encoded by a gene in the mtDNA as the cause of this disorder?arrow_forwardAlbinism, caused by a mutational disruption in melanin (skin pigment) production, has been observed in many species, including humans. In 1991, and again recently in 2017, the only documented observations of an albino humpback whale (named “Migaloo”) were observed near New South Wales. Recently, Polanowski and coworkers (Polanowski, A., S. Robinson-Laverick, and D. Paton. (2012). Journal of Heredity 103:130–133) studied the genetics of humpback whales from the east coast of Australia, including Migaloo. (a) Do you think that Migaloo’s albinism is more likely caused by a dominant or recessive mutation? Explain your reasoning. (b) What data would be helpful in determining the answer to part (a)?arrow_forward
- DNA profiling has been used to verify pedigrees of valuable animals such as show dogs, racing greyhounds, and thoroughbred horses. However, the technology is much harder to apply in these cases than it is in forensic applications for humans. In particular, many more DNA markers must be examined in domesticated animals to stablish the identity or close familial relationship of two DNA samples. Why would you need to look at more polymorphic loci in these animals than you would in humans?arrow_forwardIn a study of a muscle disorder, several affected families exhibitedvision problems, muscle weakness, and deafness (M. Zeviani et al. 1990.American Journal of Human Genetics 47:904–914). Analysis of themtDNA from affected members of these families revealed that largenumbers of their mtDNA molecules possessed deletions of varyinglengths. Different members of the same family and even differentmitochondria from the same person possessed deletions of differentsizes, so the underlying defect appeared to be a tendency for the mtDNAof affected persons to have deletions. A pedigree of one of the familiesstudied is shown below. The researchers concluded that this disorder isinherited as an autosomal dominant trait, and they mapped the diseasecausinggene to a position on chromosome 10 in the nucleus.a. What characteristics of the pedigree rule out inheritance of a traitencoded by a gene in the mtDNA as the cause of this disorder?b. Explain how a mutation in a nuclear gene might lead to deletions…arrow_forwardIn a study of a muscle disorder, several affected families exhibited vision problems, muscle weakness, and deafness (M. Zeviani et al. 1990. American Journal of Human Genetics 47:904–914). Analysis of the mtDNA from affected members of these families revealed that large numbers of their mtDNA molecules possessed deletions of varying lengths. Different members of the same family and even different mitochondria from the same person possessed deletions of different sizes, so the underlying defect appeared to be a tendency for the mtDNA of affected persons to have deletions. A pedigree of one of the families studied is shown below. The researchers concluded that this disorder is inherited as an autosomal dominant trait, and they mapped the diseasecausing gene to a position on chromosome 10 in the nucleus. Q. Explain how a mutation in a nuclear gene might lead to deletions in mtDNA.arrow_forward
- In a DNA-hybridization study, DNA was isolated from wheat, labeled with 32P, and sheared into small fragments . Hybridizations between these labeled fragments and denatured DNA from different plant species were then compared. The following table gives the percentages of labeled wheat DNA that hybridized to DNA molecules of wheat, corn, radish, and cabbage. What do these results indicate about the evolutionary differences among these plants? Species Percentage of wheat DNA hybridized relative to wheat Wheat 100 Cabbage 23 Corn 63 Radish 30arrow_forwardCardigan Corgi tail length is determined by 5 genes. The genotype DDEEFFGGHH produces a tail length of 44cm, while the genotype ddeeffgghh produces a tail length of 4cm. a) Each additive allele adds how many centimeters to the tail length? b) Predict the tail length for the following genotype: DDEEFfGgHh Group of answer choices 8cm, 56cm 4cm, 12cm 8cm, 24cm 4cm, 32cmarrow_forwardImagine that Species A and Species B are closely related species. Species A has one hemoglobin gene, located on chromosome 5. Species B has two hemoglobin genes, one located on chromosome 5 and one located on chromosome 8. Based solely on this information, it is possible that the ancestor of Species A and Species B had one hemoglobin gene, and that a large-segment duplication followed by a translocation resulted in the second hemoglobin gene of Species B. True Falsearrow_forward
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