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Description: State the relative advantages and disadvantages of amnniocentesis, chorionic villus sampling, and pre implantation genetic diagnosis in the prenatal diagnosis of human genetics abnormalities.

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Biology

State the relative advantages and disadvantages of amnniocentesis, chorionic villus sampling, and pre implantation genetic diagnosis in the prenatal diagnosis of human genetics abnormalities.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section16.3: Genetic Diseases Caused By Single-gene Mutations

Problem 7LO: State whether each of the following genetic defects is inherited as an autosomal recessive,...

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match the following about Genetic testing and Screeningprompts: genetic testing, genetic screening, genetic screening programs, Genetic screening opportunities, A test with high sensitivity, A test with high specificity, Predictive tests, Pre-symptomatic tests, Predispositional tests.Answers: - indicate the presence of a causative genotype but the onset of signs and symptoms is not certain.- involves testing individuals for the genetic change underlying a condition for which there is no evidence. - is preformed cases where the onset of signs and symptoms is considered inevitable. - are offered as part of our public health service.- can show that an individual is more likely than others to develop a specified condition.- do not include conditions that show incomplete penetrance.- has a low false positive rate.- has a low false negative rate. - involves testing individuals for the genetic change underlying a condition for which there is evidence.
Define the noninvasive prenatal genetic diagnosis (NIPGD) technique ?
Describe at least two types of prenatal testing that are used to diagnose chromosomal abnormalities and involve extraction of fetal cells for karyotypes?
What are the relative advantages and disadvantages of amniocentesis, chorionic villus sampling, and preimplantation genetic diagnosis?
Explain the three methods for geneticdefect testing before birth ?
What, if any, ethical issues might arise from the widespread use of noninvasive prenatal genetic diagnosis, which can be carried out much earlier than amniocentesis or chorionic villus sampling?
List different methods used to test for genetic abnormalities.
List the diagnostic features (genetic or cytological) that are used to identify these chromosomal alterations:a. Deletionsb. Duplications
Match the following : Genetic testing Genetic screening Genetic screening programs Genetic screening opportunities A test with high senstivity A test with high specificity predictive tests Pre- symptomatic tests Pre dispositional test involves testing individuals for the genetic change underlying a condition for which there is no evidence. can show that an individual is more likely than others to develop a specified condition. indicate the presence of a causative genotype but the onset of signs and symptoms is not certain. are offered as part of our public health service. do not include conditions that show incomplete penetrance. is performed cases where the onset of signs and symptoms is considered inevitable. involves testing individuals for the genetic change underlying a condition for which there is evidence. has a low false positive rate has a low false negative rate
1.) Chronic Myelogenous Leukemia (CML)-Briefly describe the disease and provide the most common symptoms/features of the disease.-Describe the cause/s of the disease.-Using a diagram, outline the processes of the best DNA technology tools/techniques involved in the diagnosis of the disease.-Present the best therapeutic DNA technology tool/technique for the disease by describing the tool and discussing the procedure.-Identify the challenges or issues that a scientist may face for using the DNA technology diagnostic and therapeutic tools and applications you have presented.
What is preimplantation genetic diagnosis?
State who the genetic parents are and who the gestational mother is in each of the following cases:a. A man was exposed to unknown burning chemicals and received several vaccines while serving in the U.S. military in Iraq, and abused drugs for several years before and after that. Now. he wants to become a father, but he is concerned that past exposures to toxins have damaged his sperm. His wife undergoes intrauterine insemination with sperm from the husband’s brother, who has led a calmer and healthier life b. A 26-year-old woman has her uterus removed because of cancer. However, her ovaries are intact and her oocytes are healthy. She has oocytes removed and fertilized in vitro with her husband’s sperm. Two resulting embryos are implanted into the uterus of the woman’s bestfriend.c. Max and Tina had a child by IVF and froze three extra embryos. Two are thawed years later and implanted into the uterus of Tina’s sister, Karen. Karen’s uterus is healthy, but she has ovarian cysts that…