Chapter 16, Problem 26RQ

Summary Introduction

To review:

The most common sites in a protein that are phosphorylated during signal transduction cascade.

Introduction:

Signal transductionis the process in which an exchange of chemical signals takes place as a series of molecular events. Protein kinases catalyze the protein phosphorylation process thatresults in cellular responses. The binding of a ligand to the receptor produces changes which result in a signaling cascade (a chain of biochemical events along with signaling pathways). This cascade involves protein sites or subunits at which the phosphorylation takes place.