Your uncle is taking niacin to help lower cholesterol, he is taking 5 grams/day using supplements. You tell him........ keep taking it but lower the dose to 4 grams keep taking it because it can't hurt and may help to stop because it causes liver damage and to see his doctor increase the dose to 9 grams because it will work better

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Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.