you plan to carry out the syn- thesis of aspirin (acetylsalicylic acid) by reacting salicylic acid with acetic anhydride, using 85% phosphoric acid as a catalyst. In addition to aspirin, acetic acid will be a side product. Using one of the suggested online sources (such as the Sigma-Aldrich or Acros Organics websites), look up the molar masses for all of the reagents and products in this reaction. Also look up the melting points of salicylic acid and acetylsalicylic acid and the boiling points and densities of acetic anhydride and acetic acid. Your answers should include both the molar masses and the physical properties for all four reagents and products.

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter18: Carboxylic Acids
Section: Chapter Questions
Problem 18.21P
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you plan to carry out the syn- thesis of aspirin (acetylsalicylic acid) by reacting salicylic acid with acetic anhydride, using 85% phosphoric acid as a catalyst. In addition to aspirin, acetic acid will be a side product. Using one of the suggested online sources (such as the Sigma-Aldrich or Acros Organics websites), look up the molar masses for all of the reagents and products in this reaction. Also look up the melting points of salicylic acid and acetylsalicylic acid and the boiling points and densities of acetic anhydride and acetic acid. Your answers should include both the molar masses and the physical properties for all four reagents and products.

ОН
H;PO4
ОН
+
+
H3C
`CH3
H3C
ОН
HO.
`CH3
Salicylic acid
Acetic anhydride
Acetylsalicylic acid
Acetic acid
Transcribed Image Text:ОН H;PO4 ОН + + H3C `CH3 H3C ОН HO. `CH3 Salicylic acid Acetic anhydride Acetylsalicylic acid Acetic acid
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