You are designing a study comparing Treatments A and B. You expect an enrollment rate of 150 subjects per year. From previous data, you expect exponential distributions for the survival times of each treatment, and that treatment B's mean survival time is 3 years. You want to detect that Treatment A will have a 4 year mean survival time, using a two-sided log-rank test with 90% power and an alpha of 0.05. Assuming an enrollment stage of 5 years, how long should the study be? If you use a statistical program to solve this, please include the code.

College Algebra
1st Edition
ISBN:9781938168383
Author:Jay Abramson
Publisher:Jay Abramson
Chapter6: Exponential And Logarithmic Functions
Section6.8: Fitting Exponential Models To Data
Problem 3TI: Table 6 shows the population, in thousands, of harbor seals in the Wadden Sea over the years 1997 to...
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You are designing a study comparing Treatments A and B. You expect an enrollment rate of 150 subjects per year. From previous data, you expect exponential distributions for the survival times of each treatment, and that treatment B's mean survival time is 3 years. You want to detect that Treatment A will have a 4 year mean survival time, using a two-sided log-rank test with 90% power and an alpha of 0.05. Assuming an enrollment stage of 5 years, how long should the study be? If you use a statistical program to solve this, please include the code.

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