write the balanced equation and the stepwise mechanism for the Friedel-Crafts acylation of anisole using acetic anhydride with aluminum chloride acting as catalyst. Write the complete mechanism for both para-substitution and meta-substitution, including all the resonance structures for the sigma complex for each mechanism. Explain why para substitution, not meta substitution, is preferred in this reaction.
write the balanced equation and the stepwise mechanism for the Friedel-Crafts acylation of anisole using acetic anhydride with aluminum chloride acting as catalyst. Write the complete mechanism for both para-substitution and meta-substitution, including all the resonance structures for the sigma complex for each mechanism. Explain why para substitution, not meta substitution, is preferred in this reaction.
Macroscale and Microscale Organic Experiments
7th Edition
ISBN:9781305577190
Author:Kenneth L. Williamson, Katherine M. Masters
Publisher:Kenneth L. Williamson, Katherine M. Masters
Chapter38: Grignard Synthesis Of Triphenylmethanol And Benzoic Acid
Section: Chapter Questions
Problem 1Q
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write the balanced equation and the stepwise mechanism for the Friedel-Crafts acylation of anisole using acetic anhydride with aluminum chloride acting as catalyst. Write the complete mechanism for both para-substitution and meta-substitution, including all the resonance structures for the sigma complex for each mechanism. Explain why para substitution, not meta substitution, is preferred in this reaction.
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