Would you expect methoxide ion to be a better nucleophile if it is dissolved in CH3OH or if it is dissolved in DMSO? Why?

7. Draw resonance contributors for the following two anions. Indicate which anion is a stronger base. N N 8. a) How many monobromination products (constitutional isomers) would be obtained from the radical bromination of methylcyclohexane? b) Which product would be obtained in the greatest yield? c) Which product would be obtained in the lowest yield?

Why are NH3 and CH3NH2 no longer nucleophiles when they are protonated?

There could be one or more than one answer. Please help.

Which reagent(s) will result in the nucleophile attacking the more substituted side of an epoxide? Choose all that apply. O1. O1. LICH2CH3 I. HCI II. H20, H2SO4 IV. LIAIH4

1. would you expect the relative rate of SE2 reactions to be faster or slower if a molecule of chlorine is used instead of bromine? Explain your reasoning? 2. why is the first step in an electrophilic aromatic bromination so much more endothermic than the first step in an electrophilic addition of alkene?

Which of the following alkyl halide reacts fastest in an E2 reaction? Br... Br Br Br

During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important. Generally, these reactions are done by slowly adding the alkylating agent to the aromatic component. What is the advantage of mixing the ingredients in this order rather than slowly adding the aromatic component to the alkylating agent? + AICI3 + AICI3 add add slowly slowly

A student wanted to know whether the greater proximity of the nucleophile to the C-2 carbon in the transition state is what causes the 1,2-addition product to be formed faster when 1,3-butadiene reacts with HCl. Therefore, she decided to investigate the reaction of 2-methyl-1,3-cyclohexadiene with HCl. Her friend told her that she should use 1-methyl-1,3-cyclohexadiene instead. Should she follow her friend’s advice?

Which nucleophile(s) is also a strong base? a) CH3MgBr b) LiAlH4 c) CHCH2OH d) Both CH3MgBr and LiAlH4