Q: Adding acetophenone slowly to a cold solution of LDA produces the enolate of acetophenone; but…
A: SOLUTION: Step 1: The organic reaction in which a chemical compound containing a carbonyl group acts…
Q: In the synthesis of p-nitroacetanilide, what is the purpose of adding glacial acetic acid? To…
A:
Q: When ethyl bromide is added to potassium tert-butoxide, the product is ethyl tert-butyl ether. What…
A: Reaction is:
Q: Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone…
A: enolate attacks the carbonyl electrophile and forms enone Generally this is resembles to aldol…
Q: Why does phenol or aniline react with benzene diazonium chloride during a coupling reaction, but…
A: It can be easily explain by with help of mechanism. In case of phenol and aniline the benzene ring…
Q: Why is the product in the synthesis of methyl benzoate can be extracted with a sodium carbonate…
A: Hey, since there are multiple questions posted, we will answer first question. If you want any…
Q: We used biphenyl instead of benzene for Friedel-Crafts alkylation. What would you predict the major…
A: A Friedel-Crafts reaction is an organic coupling reaction involving an electrophilic aromatic…
Q: I have questions about p-nitroaniline: Please answers all and details Why we are not starting from…
A: Electrophilic substitution reaction is defined as the reactions in which an electrophile is attacked…
Q: What is the mol ratio of acetanilide and para nitroacetanilide in para nitroacetanilide synthesis
A:
Q: Why is the presence of acid necessary in the reaction of carbonyl compounds with certain…
A: Reaction of carbonyl (suppose acetone) with nucleophile like 2,4-dinitrophenyl hydrazine follows…
Q: Why does the synthesis of grignard reagents require ethers when the synthesis of organolithium…
A: During the synthesis of any organometallic compound, we certainly require a solvent to dissolve the…
Q: Why an anhydride is more reactive than a carboxylic acid?
A: There are many carboxylic acid derivatives present and acid anhydride is now of those derivates. The…
Q: Which of the following reagents will not undergo a substitution reaction with the benzenediazonium…
A: this a substitution reaction of benzenediazonium chloride salt.
Q: Which of the following reagents will not undergo a substitution reaction with the benzenediazonium…
A: Those reagents which show substitution reaction with benzenediazonium chloride salt are given below…
Q: Write mechanisms for the reactions of aniline with acetyl chloride and with acetic acid, to give…
A:
Q: reaction of 4-bromoacetanilide to 4-bromo-2-chloroacetanilide, why is the amido (rather than the…
A: Given-> 4-bromoacetanilide --> 4-bromo-2-chloroacetanilide
Q: Which of the following reagents will not undergo a substitution reaction with the benzenediazonium…
A: Given A. KIB. H3PO3 , H2OC. H3PO2 , H2OD. CuCNE. Cu2O, Cu2+, H2OReagents will not undergo a…
Q: What's the difference between hydrolysis step of preparation of p-nitro acetanilide when using…
A: Introduction: An electrophilic aromatic substitution reaction is the reaction in which an…
Q: What compounds can be best combined with arendiazonium salts? Why?
A: Arene diazonium salts are one of the combinations of organic and inorganic components. It is formed…
Q: Draw the possible products of the diazo coupling of benzenediazonium chloride with each of the…
A:
Q: What are the possible sources of error in the nitration of acetanilide to prepare…
A:
Q: Which of the following can be used for ring-opening reactions of epoxides? a Water b Grignard…
A: A multiple choice question based on introduction to organic chemistry that is to be accomplished.
Q: N-Methylbenzamide, an isomer of acetanilide, when allowed to react with HNO3/H2SO4 gives a different…
A:
Q: Result obtained in the reaction between acetylene and ammoniacal silver chloride
A: Acetylene is the simplest and first Molecule of alkyne family, with Molecular formula of C2H2 , its…
Q: What is indicated by the result obtained in the reaction of acetanilide with bromine in acetic acid?…
A:
Q: What is the principle behind a Grignard synthesis involving a benzophenone to make phenylmagnesium…
A: Grignard reagent is RMgX where carbon is attached to a magnesium halide. Reaction of Grignard…
Q: reactivities of the following compounds according to the SN1 reaction. please explain why a) Methyl…
A: Many reaction mechanisms are studied in organic chemistry. The nucleophilic substitution mechanism…
Q: why the acetylation requires one mole of acetic anhydride per mole of aniline, though acetic…
A: In the organic synthesis, suitable reagent converts the reactant into products. Reagents attacks…
Q: Explain the Reaction of Organometallic Reagents with Epoxides ?
A: Organometallic reagents are those reagents that have a bond between the carbon atom and the metal.…
Q: Why does phenol or aniline react with benzene diatonic chloride during a coupling reaction, but…
A:
Q: The reaction of an alkyl chloride with potassium iodide is generally carried out in acetone to…
A: Since potassium iodide is soluble in water while potassium chloride is not, the alkyl chloride will…
Q: Methyl sulfate is a better o-methylating agent than methyl halides. Why ?
A: Methyl sulfate is a well known reagent which is used for the ortho methylation of amines, phenols…
Q: Which synthesis of a grignard reagent would fail to occur as written
A: Grignard reagent can be prepared from alkyl or aryl or vinyl halides and Mg metal . During the…
Q: Which solvent would make the bromination through electrophilic aromatic substitution faster?…
A: Generally bromination through electrophilic aromatic substitution is more efficient in polar…
Q: What is one method for preparing an epoxide and write out the reaction.
A: Epoxide can be prepared by the reaction of an alkene with peroxide like m-CPBA.
Q: Friedel-Crafts acylation
A:
Q: A greener alternative to bromination with elemental bromine is the reaction of the acetanilide with…
A: Ammonium ceric nitrate is an inorganic compound. It's molecular formula is (NH4)2Ce(NO3)6. It is…
Q: How do you account for the fact that N-phenylacetamide (acetanilide) is less reactive toward…
A: Given statement, N-phenylacetamide is less reactive toward electrophilic aromatic substitution…
Q: Explain the Reaction of Acetylide Anions with Epoxides ?
A: The Reaction of Acetylide Anions with Epoxides has to be explained.
Q: why the –NHCOCH3 group in acetanilide is only moderately activating while the -NH2 group in aniline…
A: As per regulation only one question can be answered. Besides question 2 is incomplete.
Q: isolate
A: Dear student I have given answer to your question in the image format.
Q: Can acetyl chloride be used in place of acetic anhydride in the synthesis of acetanilide with…
A: Synthesis of Acetanilide from acetyl chloride and aniline.
Q: How do you explain the difference in colors between the hydrazone product formed from simple…
A: we can identify carbonyl group of aldehydes or ketones by 2,4 DNP test. If compound give solid…
Q: Which would be the best choice of base for a Claissen reaction with propyl acetate? sodium propoxide…
A: When two molecules of an ethyl acetate undergo condensation reaction, in presence of sodium ethoxide…
Q: From the lists of available reagents select the one(s) you would use to in a preparation of…
A: Grignard can change to the required product.
Q: Organolithium reagents (RLi) are strong bases that readily react with acidic protons. Why aren't…
A: A strong acid is an acid that dissociates to make protons available for reaction. Acid mainly…
Q: Although nitration of aniline is slow and gives mostly meta substitution, nitration of acetanilide…
A:
Q: Rank each of the following compounds in decreasing order of reactivity towards Friedel-Crafts…
A: The aromatic compounds with electron rich sites undergoes the Friedel crafts alkylation. In case of…
Step by step
Solved in 2 steps with 2 images
- 1. The starting material dissolves in dilute HCI, but the product acetanilide does not. Why?Explain how the class I carbonyl compound reacts? What will be the product when ethylamine and propyl amine reacts with acetyl chloride? Why only one amide obtained after the reaction of acetyl chloride with a mixture of ethylamine and trimethylamine? Excess amine is required in the reaction of acetyl chloride with amine whereas excess alcohol is not required in the reaction of acetyl chloride and alcohol. Why? List the following ester in order of decreasing reactivities towards hydrolysis with reason: Methyl benzoate, p-nitro methyl benzoate and p-methoxy methyl benzoateWhen acetophenone, hydroxelamine hydrochloride, and sodium hydroxide are reacted to synthesize acetophenone oxime, why is it necessary to add hydrochloric acid after the reaction to make it acidic?
- Explain the reaction for the formation of acetal and hemiacetal. Explain why N,N-disubstituted amide is less acidic than ester. Why only methyl ketone do undergoes haloform reaction. LDA is the base of choice for carbonyl compound to completely convert into enolate. Why?Why is only one amide obtained from the reaction of acetyl chloride with an equivalent of ethylamineand an equivalent of triethylamine?N-Methylbenzamide, an isomer of acetanilide, when allowed to react with HNO3/H2SO4 gives a different product from what is obtained from acetanilide. What is the structure of the mononitrated product? Why is it produced?
- Write out the steps necessary to convert the compound on the left into the compound on the right using a diazonium salt at least onceChoose one reaction that would react with oxybenzone to generate another productExplain why a secondary amine forms a nitrosamine rather than a diazonium ion when it reacts with a nitrosonium ion.