Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Why can we say that having a pure non- competitive inhibitor present is similar to just having less enzyme present?
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- Draw the graphs representing activity behavior for each uncompetitive Inhibition, non-competitive Inhibition, and competitive Inhibition. Please use a ruler, draw, photograph, and insert the image in this document. Label x and y axes, Km and Vmax.arrow_forwardIn an experiment, three batches of the same enzyme were incubated with 5 mM of substrate and 2 mM of inhibitor. In each batch, the inhibitor was of a different type: a.Batch 1: competitive inhibitor b.Batch 2:uncompetitive inhibitor c.Batch 3:non-competitive inhibitor Assuming that Vmax = 80 mM s', Km = 8 mM, and Kiof all three inhibitors was 10 mM, which of the inhibitors was the most efficient on Vo? Explain your answer.arrow_forwardWhat effect will competitive inhibitor have on the apparent Km of an enzyme for its substrate?arrow_forward
- 22.arrow_forwardIn a Lineweaver-Burk plot of an enzyme inhibited with a competitive inhibitor, how does the plot change with increasing inhibitor concentration? a) the slope decreases and the y-intercept stays the same b) the slope increases and the y-intercept stays the same c) the slope decreases and the y-intercept increases d) the slope increases and the y-intercept descreases e) none of the abovearrow_forwardWhich of the following are characteristics of catabolic metabolic pathways? (Choose all correct answers). Overall oxidation of initial substrates so redox reactions involve use of NAD+ as oxidizing agent, converted to NADH. Large initial substrates are broken down to smaller final products. Overall reduction of intial substrates so redox reactions involve use of NADPH as reducing agent, converted to NADP+. The pathways are overall exergonic (negative delta G). Net production of ATP as a result of the pathway. Essentially irreversiblearrow_forward
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