Why can imputation lead to bias in GWAS studies?

Q: What is the correct citation for this article https://doi.org/10.1016/j.pep.2018.03.006 based on the…

A: A citation is a reference to the knowledge source that you used in your analysis. In your job, if…

Q: How is NBT/BCIP utilized in western blotting?

A: Western blotting is a technique used for the  detection of specific proteins in a given sample. It…

Q: I struggled with ati teas 7 reading section. Can you help me how to study the ati teas 7 reading…

A: Your role as a nurse requires you to have a firm grasp of medical literature, patient records, and…

Q: explain why controls are crucial in biological studies?

A: An experiment is a research approach to validate a hypothesis based on evidence and results. An…

Q: How do you interpret Blastn results with 0 % query coverage and 100 % identity?

A: BLAST stands for basic local alignment tool which is a program and algorithm for the comparison of…

Q: Explain the concept of method validation by describing five important validation facets?

A: Analytical methods development and validation are an essential part of analytical procedures in…

Q: Explain briefly the hershey-chase experiment?

A: The confirmation that DNA is the genetic material was given by the Hershey-Chase experiment. The…

Q: Why are Nursing Innovations important in COVID-19? How is this done by nurses? What are important…

A: Nursing innovation is introduction of novel processes, services and products to improve patient…

Q: How can performance bias be reduced in animal experiments in conducting vivo experiments

A: In this question it is to describe that how can performance bias be reduced in animal experiments in…

Q: Briefly elaborate Major considerations in dosage form design with example" ?  Please briefly explain…

A: 1. preliminary research 2. Drug and drug product stability   preliminary research Before a…

Q: When we need to perform Southern, Western and Northern blotting? How they are different from one…

A: Blotting is the technique used to transfer the DNA, RNA, or protein sequence on a carrier membrane…

Q: Why are appropriate transducer orientation and image standardization important in vascular…

A: Importance of transducer orientation in Vascular Sonography: *In order to get an exact image, the…

Q: s th

A: Answer-- Meselson and Stahl experiment use N15 in E.coli by density gradient centrifugation.This…

Q: What are the advantages of normalizing against a reference gene in qPCR?

A: PCR stands for Polymerase Chain Reaction, and it is a widely used method that allows us to make many…

Q: Why ELSI Program is important for issues arising from the HGP ?

A: HGP stands for human genome project. It is an international scientific research project. This…

Q: Genotyping of few SNPs in many patients?

A: SNP's stands for Single Nucleotide Polymorphism which usually occurs due to some point mutation. Any…

Q: In a cotransduction experiment involving P1, the cotransductionfrequency was 0.53. How far apart are…

A: Transduction is the process of the transferring foreign DNA into the host cell by viral vector. T4…

Q: What is abiogenesis? Why the Urey-Miller experiment so important? How did the experiment work?…

A: Introduction :- According to the theory of abiogenesis, the earliest life forms produced were…

Q: What is a mouse model for human disease?

A: Humans are the multicellular eukaryotic organism belonging to the kingdom Animalia and class…

Q: 1. How Spallanzani’s experiment different from Needham?

A: John Needham hoped to eradicate all pre-existing microbes by briefly boiling broth flavoured with…

Q: How can AI and ML be used to identify biomarkers?

A: AI stands for Artificial Intelligence while ML stands for Machine Learning. Machine learning is a…

Q: How is complementation a useful technique in understanding allelism and gene function

A: When two varieties of an entity have separate homozygous recessive mutations, if they both display…

Q: How can linkage disequilibrium mapping sometimes provide a much higher resolution of gene location…

A: Linkage analysis rely on co inheritance of functional polymorphism, In linkage analysis, there are…

Q: How SNPs can be detected and used for diagnosis and treatmentof disease ?

A: The study of genomes' architecture, functioning, development, sequencing, and modification is the…

Q: Discuss the major challenges when using microarray techniques to study differential gene expression.…

A: Microarray is a powerful laboratory technique used in genomics and molecular biology to…

Q: Define RFLPs and give their significance.

A: RFLP stands for Restriction fragment length polymorphism. Restriction fragment length polymorphism…

Q: How do you see regulatory frameworks evolving to address these sophisticated types of collusion and…

A: Currently, regulatory frameworks in health science are primarily focused on ensuring the safety and…

Q: What is the utility of understanding the genetic basis of susceptibility to COVID-19 for medicine…

A: To date, 3p21. 31 is the only genetic region significantly associated with severe COVID-19. Having…

Q: illustrate several applications of the chi-square test pertinent to genetics.

A: A chi-square test (X2) is a statistical procedure which is used in decision making in case of…

Q: Should the exposome field focus exclusively on measuring chemicals derived from exogebeous sources…

A: The term "exposome" describes all of an individual's lifetime environmental exposures, including…

Q: Elaborately define the major considerations in dosage form design with example?

A: Drug substances are rarely administered alone; instead, they are combined with one or more…

Q: give an example of experimental research . Why this resesrch is beneficial?

A: An experimental research is defined as the investigation to find the cause-effect relationship…

Q: Explain the multiple testing problem of GWAS - why do we need such a small p-value to achieve…

A: Imagine you're flipping a coin a bunch of times. If you only flip it once, getting heads might not…

Q: Define the historical significance of Southern blotting ?

A: DNA profiling is the process of determining an individual's unique DNA pattern. DNA profiling can…

Q: People with severe depression, mild depression, or no depression are included in GWAS research. Why…

A: A genome-wide association study (GWAS) is an approach used in genetics research to associate…

Q: Explain how COVID-19 can be detect using molecular based

A: Given: Need to find how the COVID-19- can be detected using molecular based technology. Coronavirus…

Q: explain how covid is the biggest healthcare challenges facing the world today?

A: Introduction The SARS-CoV-2 virus causes Coronavirus Disease (COVID-19), an infectious disease. The…

Q: How is a genome-wide association study carried out?

A: Deoxyribonucleic acid (DNA) is a genetic material of most organisms. DNA contains the instructions…

Q: Briefly Explain different applications of western blotting. Please explain at your own words.

A: A western blot is an analytical molecular biology laboratory method that is used in the detection of…

Q: In conducting feeding trials to evaluate the effect of feed additives: a. Why is it important to…

A: In conducting a feeding trial to evaluate the effect of a feed additive, it is important to…

Q: Do you think IPRs are safeguarding the breeders ?

A: Plant breeding is a time-consuming and costly biological science, yet plant varieties may be cheaply…