If you can answer both of these I would greatly appreciate it. Also an explanation Which statement about glycolytic kinases is FALSE?Reactions catalyzed by kinases in the first stage of glycolysis use ATPas the donor of the phosphate group, while in the second stage theyuse ADP as the acceptor of the phosphate group.Phosphofructokinase catalyzes the committed step of glycolysis inmuscle cells.Allosteric regulation of liver pyruvate kinase depends on the energycharge of the cell.The expression of glycolytic kinases is controlled by the partial pressureof oxygen in tissues.O All of the glycolytic reactions catalyzed by kinases are irreversible. What process takes part in NAD* regeneration?metabolism of fructosesynthesis of triose phosphatesmetabolism of pyruvatesynthesis of pyruvatealdolase reaction

In the glycolysis pathway, glucose is converted to pyruvate (aerobic condition) or lactate (anaerobic condition, along with the production of a small quantity of energy. All the reaction steps take place in the cytoplasm.1. Glycolytic Kinases enzymes are involved in multiple phosphorylation reactions in glycolysis. Step 1 is the stage of investment. For each mol of glucose, 2 mols of ATP are absorbed. Glucose is converted into fructose-1,6-bisphosphate. Glucose is trapped within the cell and, at the same time, transformed into an unstable shape that can be quickly broken down into 3-carbon units. Step 2 fructose-1,6-bisphosphate is divided into 2 3-carbon units of glycerladehyde-3 phosphate. Step 3 is the stage of harvesting. 4 mols ATP and 2 mols NADH is extracted from each of the initial glucose moles. This ATP is the product of Glyceraldehyde-3-phosphate substrate-level phosphorylation, which is oxidised to pyruvate. A total of 10 enzymes catalyzes the 10 steps of the glycolysis pathway. Out of these 10, 3 reactions catalyzed by hexokinase, phosphofructokinase, and pyruvate kinase are virtually irreversible; hence, these enzymes would be expected to have regulatory as well as catalytic roles. The conversion of 1,3-Bisphosphoglycerate to 3-phosphoglycerate is catalyzed by 1,3-Bisphosphoglycerate kinase which is a reversible reaction. Hence, last option is false, as all glycolytic kinases are not irreversible. 2. In erythrocytes and oxygen-deprived tissue, pyruvate persists within the cytoplasm and transforms to lactate, a mechanism known as anaerobic glycolysis. This final reaction enables the regeneration of NAD+, a cofactor that must be accessible at adequate intracellular concentrations in order to remain favorable to the earlier reactions of glycolysis. However, compared to oxidative phosphorylation, anaerobic glycolysis is significantly less efficient, providing net production of only 2 ATP per glucose molecule. Hence, the correct option is "metabolism of Pyruvate"