Which of the following explains why alpha-amino acids, the building blocks of proteins, are nearly 1000 times more acidic thanaliphatic carboxylic acids?H3N.R.An a-amino acidAn aliphatic acidpK, 5pKa = 2O Inductive effects of the aliphatic group destabilize the conjugate base.O Inductive effects of the amino group help stabilize the conjugate base.O Inductive effects of the aliphatic groups help stbilize the conjugate base.O Inductive effects of the amino group destabilize the conjugate base.

Strong acids are those in which the conjugate base of this acid is stable. As amino are stronger…

Answered: Which of the following explains why…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section23.6: Reactions With Acids

Problem 23.8P

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Acid-Base Equilibria Many factors contribute to the acidity of organic compounds. Electronegativity, resonance, induction, hybridization, aromaticity, and atomic size, all play a role. In the following comparisons, you are asked to identify the factor(s) that would be most important to analyze when predicting relative acidity, and then to predict the trend in acidity and pKa values. For each of the following pairs of compounds answer the following two multiple-choice questions. 1. What factor(s) are the most important to consider when predicting the relative acidity of the two compounds? a. Electronegativity of the atom possessing the hydrogen. b. Resonance stabilization of the anionic conjugate base. c. Inductive stabilization of the anionic conjugate base. d. Hybridization of the atom possessing the hydrogen. e. The atomic size of the atom possessing the hydrogen.
Dicarboxylic acids have two dissociation constants, one for the initial dissociation into a monoanion and one for the second dissociation into a dianion. For oxalic acid, HO2Câ€”CO2H, the first ionization constant is pKal = 1.2 and the second ionization constant is pKa2 = 4.2. Why is the second carboxyl group far less acidic than the first?
h) 22:00 HO Br K₂CO3 (weak base)
O BIOLOGICAL MACROMOLECULES Classifying amino acids Classify each of the amino acids below. Note for advanced students: none of these amino acids are found in normal proteins. H3N -CH-COO H3N -CH COO CH2 CH, H3N -CH- COO CH2 CH2 NH3 CH3 CH3 (Choose one) ▼ nonpolar polar basic nonpolar polar neutral polar acidic H3N -CH-cOO HạN -CH-COO polar basic CH2 CH2 CH2 CH2 NH (Choose one) polar acidic polar basic 5 சி II
Benozic acid (C6H5COOH) has a pKa of 4.20. a. What is the ratio of the acid to its conjugate base at a pH of 2.20?
O 18. Draw the predominant ionization form of the amino acid tyrosine at pH = 10. Tyrosine is shown in its fully protonated "low pH" form on the left. Love sono H pKa - 8.95 pka-10.46 pKa-2.18 H -H
Consider acid acid and trifluoroacetic acid. The pKa of acetic acid is 4.75. Which of the statements below is false? F3C OH HO acetic acid trifluoroacetic acid O The pka of trifluoroacetic acid is larger than 4.75 O The conjugate base of trifluoroacetic acid is stabilized inductively The conjugate base of acetic acid is stabilized by resonance O The pka of trifluoroacetic acid is lower than 4.75 O The conjugate base of trifluoroacetic acid is stabilized by resonance QUESTION 40 What product/s) islare) formed in the followina reaction
H H3C. „N. CH3 CH3 CH3 Diisopropylamine is a weak organic base has a pk of 2.93 at 25 °C. Write the balanced chemical equation for the base ionization of (Me2CH)2NH in water and the corresponding K₁ expression.
Amino acids have different protonation states at different pH. The protonation states of the amine and carboxylic acid functional groups can vary at different pH. In addition, the side chain can have different ionic states. Choose the protonation state of lysine at physiological pH. H₂N- H NH₂ I OH H₂N. H₂N H 0=6 NH₂ IV NH₂ || OH H₂N. H H₂N H NH₂ O V NH₂ |||
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En la reacción de autoprotólisis de agua: 2H₂O(0) H₂O*(aq) + OH (aq); los pares conjugados ácido-base corresponden a: Seleccione una: O a. par 1: H₂O* y OH"; par 2: OH y H₂O O b. par 1: H3O* y OH; par 2: OH y H₂O* Oc par 1: H₂O y H₂O; par 2: H₂O* y OH O d. par 1: H3O* y OH; par 2: H₂O* y H₂O par 1: H₂O y OH; par 2: H₂O y H3O+ O e.
What is the conjugate base of HSO4?

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