Which of the following explains why alpha-amino acids, the building blocks of proteins, are nearly 1000 times more acidic than aliphatic carboxylic acids? H3N, R OH OH R An a-amino acid An aliphatic acid pk, = 5 pK, = 2 O Inductive effects of the aliphatic group destabilize the conjugate base. O Inductive effects of the amino group help stabilize the conjugate base. O Inductive effects of the aliphatic groups help stbilize the conjugate base. O Inductive effects of the amino group destabilize the conjugate base.

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Consider the proton transfer reaction between the following compounds. + لا F F OH 12 F

F Below are four molecules that are pH sensitive: F O Structure A OH F O Structure OH Br O Br Structure C 1. Sort the given molecules in the increasing of pka values. OH 2. What was your choice for strongest acid? Explain your answer. Br Br Structure D OH

Using their Ka values, what is the pKb1 of  0.10 M chloroacetic acid 0.20 M carbonic acid 0.40 M citric acid

The structure of the amino acid tyrosine is shown below in its completely protonated form. PK 16 OH CH2O : ד pK₂ 2 PK 9 H₂N C-C-OH H

The structure of the amino acid tyrosine is shown below in its completely protonated form. PK 16 OH CH2O : ד pK₂ 2 PK 9 H₂N C-C-OH H

The protonated amine group in the structure below has a pka of 9.5. ОН СНз OH CH3 +. N. N-H H30* H2O + + CH3 CH3 Structure A Structure B Which form of the compound predominates at a pH of 2.7? [Select ] Which form of the compound predominates at a pH of 10.9? [ Select ] Which structure has a greater ability to diffuse across a cell membrane? [ Select ]

The pka's of the ascorbic acid are pka1 = 4.10 and pka2 = 11.80. If the net charge of ascorbic acid is exactly -1, what is the pH of the solution? Use 2 decimal places.

Consider the following five weak acids: Succinic acid: pKa = 4.16 НOBr: Ka%3D 2.06 х 10°9 Dinicotinic: pKą = 2.08 Nitrobenzoic: Ka = 6.95 x 10-3 Saccharin: pKa = 11.68 Order these acids from the strongest (1) to the weakest (5) Dinicotinic [Choose] Saccharin [ Choose] Nitrobenzoic [Choose] НOBr [Choose] Succinic acid [Choose]