Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4? MTS Tris (tris(hydroxymethyl)aminomethane): pK₁ = 8.0 Phosphate: pKal = 2.16 pKa2 = 7.21 pK₁3 = 12.32 Leucine: pKal= 2.328, pKa2=9.744 HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pka2 = 7.5

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Chapter9: Acids, Bases, And Salts
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5. Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4?
MTS88,0
MACELI
A. Tris (tris(hydroxymethyl)aminomethane): pKa = 8.0
3. Phosphate: pKal = 2.16 pKa2 = 7.21 pka3 = 12.32
C. Leucine: pKal= 2.328, pKa2=9.744
D. HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pKa2 = 7.5
Transcribed Image Text:5. Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4? MTS88,0 MACELI A. Tris (tris(hydroxymethyl)aminomethane): pKa = 8.0 3. Phosphate: pKal = 2.16 pKa2 = 7.21 pka3 = 12.32 C. Leucine: pKal= 2.328, pKa2=9.744 D. HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pKa2 = 7.5
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