Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Which is the definition of 'retrograde' with respect to membrane trafficking?
movement from the endosome to the lysosome |
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movement from the ER to the Golgi to either the plasma membrane or the endosome/lysosome |
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movement from the cytoplasm to the nucleus |
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movement from the Golgi to the ER |
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- What is the plasma membrane made of? How does this affect the movement of lipid-soluble and non-lipids through the cell?arrow_forwardWhich of the following mechanisms is used to return mis-sorted proteins from the Golgi apparatus to the endoplasmic reticulum? O Receptor mediated endocytosis O COPII coated vesicles O COPI coated vesicles O Retrograde transport O Autophagy « Previousarrow_forwardWhich of the following membrane components is found in the greatest abundance on the inner leaflet of eukaryotic vesicles produced for secretion by the Golgi apparatus? phosphatidylethanolamine glycolipids phosphatidylinositol cholesterol phosphatidylserinearrow_forward
- If cells are treated with colchicine, a drug that promotes microtubule disassembly, the location of the ER and Golgi both change dramatically. Rather than being spread out quite widely through the cytoplasm, the ER appears to collapse into the area near the nucleus. (Recall that the ER membrane and the outer nuclear envelope are continuous with one another). In contrast, the Golgi stacks disperse from their usually more compact, central location to areas all over the cell. However, if colchicine is removed, and microtubules are allowed to reassemble, both organelles eventually return to their normal distribution in the cells. How do you account for the change in distribution of the ER & Golgi when microtubules are depolymerized? What protein(s), other than tubulins, allow normal cellular organization to be restored once colchicine is removed? (answer should include information to explain both the ER & Golgi)arrow_forwardA toxin produced by a certain species of snail can interfere with the formation of the Golgi Apparatus. The toxin prevents the formation of the trans face of this organelle. This toxin would prevent . Group of answer choices Transport of lipids from the smooth ER to the Golgi Apparatus Digestion of malformed proteins by the lysosomes Transport of proteins to the plasma membrane for export out of the cell Reception of proteins from the rough ERarrow_forwardA vesicle that is created by the cell "eating" a large molecule from outside the cell is called a O endosome peroxisome phagosome lysosomearrow_forward
- Trace the pathway of a protein embedded in the membrane from the nucleus to becoming part of the lysosome. Please number the steps in the order they occur in the cell. For full credit, you must describe each organelle and transport vesicle the product moves through and describe in detail how each organelle modifies the protein.arrow_forwardWhich is NOT a general function of the cellular cytoskeleton? Regulation of intracellular transport Regulation of cell motility and cellular contraction Assembly of DNA into chromatin Separation of the chromosomes during mitosis Structural support for the cellarrow_forwardWhy do cancer cells treated with vitamin E succinate appear to be more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than normal cells? cancer cells often have an alkaline cytosol, which destabilizes the alkaline lysosomes cancer cells often have an alkaline cytosol, which destabilizes the acidic lysosomes cancer cells often have an acidic cytosol, which destabilizes the alkaline lysosomes cancer cells often have an acidic cytosol, which destabilizes the acidic lysosomes all of the abovearrow_forward
- Which of the following membrane components is found in the greatest abundance on the inner leaflet of eukaryotic vesicles produced for secretion by the Golgi apparatus? phosphatidylethanolamine phosphatidylinositol phosphatidylcholine phosphatidylserine cholesterolarrow_forwardWhich of the following requires a specific interaction with the molecules or substance it is going to take into the cell? fluid-phase endocytosis transcytosis PRE pinocytosis phagocytosis receptor-mediated endocytosisarrow_forwardProteins destined for which of the following destinations are transported through vesicles/the Endomembrane system? (i.e. not transported via post-translational import)arrow_forward
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