When traders and missionaries first went to the Hawaiian Islands, thenatives there experienced severe disease and high mortality ratesfrom smallpox, measles, and certain STDs. Explain whatimmunologic factors are involved in the devastating effects of newdiseases in previously unexposed populations.

Your grandparents step in and force Uncle Sean to get Matthew vaccinated. Having never been immunized in his life thus far, Matthew gets HepB, DTPa, Hib, Polio, Pneumococcal, Rotavirus, MMR, Meningococcal vaccines all in one go. While overseas however, Matthew still became ill. He had difficulty breathing one night and needed to be hospitalized. He was diagnosed with Streptococcus pneumoniae induced pneumonia and required intravenous antibiotic therapy.   A. Is it normal for a 2 year old like Matthew to have not received any vaccines? B. Despite receiving the Pneumococcal vaccine, Matthew still caught pneumonia. How could this happen?

Smallpox is the only infectious disease eradicated because so many people were vaccinated worldwide. Why do you think we have not been able to eradicate other infectious diseases (like measles or polio) for which we have effective vaccines?

. Explain how smallpox is transmitted and how its hallmark sign is produced in skin. When was smallpox declared eradicated? How does monkeypox differ from smallpox?

why can some people with HIV be symptom free for years at a time?

Do we have to get vaccinated every year against infl uenza? What eff ect will previous years’ vaccines have on the immune response to the current infl uenza strain?

Why are most unimmunized children protected against diseases such as measles?Choose one: A.  They lack the host cells for viral replication. B.  They are protected by herd immunity. C.  They have developed immunity toward the measles virus. D.  They still have circulating maternal antibodies.

HIV infection is considered to be: ○ a. high contagiousness/high virulence. O b. high contagiousness/low virulence. low contagiousness/low virulence. О с. ○ d. low contagiousness/high virulence.