Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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**Title: Retrosynthetic Analysis Question in Organic Chemistry**

**Introduction:**
When conducting retrosynthetic analysis for the target synthesis shown, determining the appropriate initial question is essential for guiding the synthesis strategy.

**Chemical Reaction Diagram:**
The diagram depicts the transformation of a terminal alkyne into a vinyl bromide. The alkyne has a triple bond between two carbon atoms, and the vinyl bromide product has a double bond adjacent to a bromine atom.

**Multiple Choice Question:**

When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask *first*?

- ○ What conditions should I use to brominate an alkane?
- ○ From what functional group can a vinyl bromide be made?
- ○ How do you convert an alkyl halide into an alkene?
- ○ How do you convert a vinyl halide into an alkyne?

**Analysis:**
Choosing the right initial question helps establish the synthesis path, focusing on the conversion of functional groups and exploring the reactions needed to achieve the target molecule.
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Transcribed Image Text:**Title: Retrosynthetic Analysis Question in Organic Chemistry** **Introduction:** When conducting retrosynthetic analysis for the target synthesis shown, determining the appropriate initial question is essential for guiding the synthesis strategy. **Chemical Reaction Diagram:** The diagram depicts the transformation of a terminal alkyne into a vinyl bromide. The alkyne has a triple bond between two carbon atoms, and the vinyl bromide product has a double bond adjacent to a bromine atom. **Multiple Choice Question:** When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask *first*? - ○ What conditions should I use to brominate an alkane? - ○ From what functional group can a vinyl bromide be made? - ○ How do you convert an alkyl halide into an alkene? - ○ How do you convert a vinyl halide into an alkyne? **Analysis:** Choosing the right initial question helps establish the synthesis path, focusing on the conversion of functional groups and exploring the reactions needed to achieve the target molecule.
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