What is the virus transmission, the morphology and the family name of the virus that causes herpes simplex virus 1 and 2?
HSV-1 and HSV-2 are transmitted by contact with an infected person having reactivation of the virus. HSV-2 is periodically shed in the human genital tract. HSV-2 can be sexually transmitted, including contact with the saliva, Both the viruses can be transmitted vertically during childbirth. Suclinical shedding is one of the main reasons for transmission. They can aslo affect areas of skin exposed to contact with an infected person.0A running in the middle.
The virus paricles were found to consist of three main parts: the core which is embedded in, a characteristic shell (capsid) and an envelope. The core showed evidence of polyhedral shape and the average diameter was 775A. Diameter of the capsid is 1050A and was found to be composed of 162 substructures arranged in an orderly manner showing axial symmetry. Capsomeres occur as hollow, elongated polygonal prisms with a hole of 40 A.
HSV-1 is characterized by three distinct morphological units . A DNA containing icosahedral capsid is surrounded by a layer known as tegument, which in turn is surrounded by a protein containing lipid bilayer, the envelope.
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