What is the result of Frameshift mutations from the insertion or deletion of nucleotides within the coding sequence?

Q: How many bases/nucleotudes make up a codon?

A: A nucleotide is a fundamental building block of nucleic acids, which include DNA (deoxyribonucleic…

Q: Which type of mutation best describes a change in a non-coding region of the genome?

A: Mutation: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to…

Q: Why is deleting one nucleotide generally more detrimental than deleting three?

A: Nucleotides are monomeric units of nucleic acids.They are phosphate esters of nucleosides and made…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: If a single strand of a gene contains 678 bases, how many amino acids result in the polypeptide…

A: The biochemical substance that is carried from the preceding generation to the succeeding generation…

Q: Why will a mistake in the RNA code alone not become a mutation?

A: A change in the genetic code is called a mutation when it becomes a permanent part of the genome of…

Q: What are the codons for the variations amino acid?

A: Amino acids are organic compounds that combine to form proteins, which are the building blocks of…

Q: What is the significance of the terminal inverted repeats oftransposons?

A: Transposons are the sequences of the nucleotides in the genome that have the ability to change their…

Q: What is the function of a stop codon?

A: Codon -- A codon is a specific type of genetic code which carries certain type of important…

Q: If the wild-type codon is GUU, which of the following single-nucleotide polymorphisms lead to a…

A: Understanding the impact of single-nucleotide polymorphisms (SNPs) on amino acid sequences is…

Q: Given the Following DNA template, TAC   CGC   TCC   GCC  GTC   GAC   AAT   ACC   ACT, write out the…

A: The DNA template is used for the synthesis of mRNA molecules. mRNA molecule is used by the…

Q: What is the biological significance of the extensive degeneracy of the genetic code?

A: Ribonucleic acid (RNA) is a nucleic acid found in both the nucleus and cytoplasm. It can be genetic…

Q: Will the exon missense mutations be more likely to be transitions or transversions? Define both in…

A: Introduction  A mutation is a change that occurs in the DNA sequence of an organism. DNA…

Q: Why can the genetic code be qualified as a “degenerate code”?

A: The genetic code is referred as the nucleotide sequence of nitrogenous base, which specifies the…

Q: What codons are used and with what frequency?

A: mRNA is translated to form proteins. mRNAs contain trinucleotides sequences that are called codons.…

Q: What causes exon shuffling?

A: Exon shuffling is a molecular mechanism for the formation of new genes. It is a process through…

Q: Which part of the central dogma is achieved by the process of translation?

A: The central dogma of molecular biology is a foundational system that depicts the flow of hereditary…

Q: How many codons are there? How many amino acids are coded by these codons?

A: We can say that Codons are basically the three-letter code that is made up of any three of the four…

Q: What mutations can be caused by a single base change in coding exons?

A: A mutation is  any kind of alteration in the DNA/mRNA sequences. It is mainly caused due to the…

Q: Explain why STR mutations are found at a much higher frequency than single nucleotide changes?

A: STR means single tandem repeat, and the mutation in the STR segments is at a very high rate .

Q: How can a silent mutation lead to “exon skipping”?

A: In a silent mutation there is a change in DNA nucleotides. If a silent mutation occurs in an exon…

Q: What role do transposons play in the process of exon shuffling?

A: Introduction  Transposons are the short highly repeated DNA sequence present in heterochromatic…

Q: Why is wobble tolerated in the third position of the codon but not in the first two?

A: Deoxyribonucleic acid(DNA) carries genetic information required for the survival of living organisms…

Q: What is base substitution in Gene Mutations ?

A: What is base substitution in Gene Mutations ?

Q: What is the minimal number of insertions/deletions of nucleotides that would result in a frameshift…

A: A mutation happens when a DNA (deoxyribonucleic acid) gene is broken or modified causing the change…

Q: Hetero Nuclear RNA or hnRNA is the unmodified transcript. What process cuts out pieces of this RNA…

A: Gene expression is the phenomenon by which information in the DNA is translated to produce a…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.