What is the multiple testing problem? Why is the Bonferroni adjustment conservative for GWAS data analysis? Suppose you are conducting two parallel and identical GWA studies (using the Affymetrix 500k GeneChip platform), one study in a European population and one in an African population. For which study would the Bonferroni adjustment be more conservative - European or African? Why?
What is the multiple testing problem? Why is the Bonferroni adjustment conservative for GWAS data analysis? Suppose you are conducting two parallel and identical GWA studies (using the Affymetrix 500k GeneChip platform), one study in a European population and one in an African population. For which study would the Bonferroni adjustment be more conservative - European or African? Why?
Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
18th Edition
ISBN:9780079039897
Author:Carter
Publisher:Carter
Chapter4: Equations Of Linear Functions
Section: Chapter Questions
Problem 8SGR
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