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What is the mechanism for the following reaction?

What is the mechanism for the following reaction?

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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What is the mechanism for the following reaction? 

### Synthesis of Indole Derivative This illustration represents a chemical reaction involving an indole derivative. 1. **Reactants:** - **First molecule (left side):** - The structure contains a benzene ring fused to a five-membered ring with a double bond and an OH (hydroxyl) group attached. - **Second molecule (middle):** - Comprises an amide group (NH₂) with a carbonyl group (C=O) attached. 2. **Reaction:** - These molecules react together, as indicated by the "+" and the arrow, to form a new product. 3. **Product:** - **Final molecule (right side):** - The benzene ring is still fused to the five-membered ring. - A NH₂ (amine) group replaces the initial OH group. This reaction shows the transformation of a hydroxyl group to an amine group within an indole framework, showcasing a common type of organic synthesis used in pharmaceutical chemistry and other chemical industries involving indole derivatives.
Transcribed Image Text:### Synthesis of Indole Derivative This illustration represents a chemical reaction involving an indole derivative. 1. **Reactants:** - **First molecule (left side):** - The structure contains a benzene ring fused to a five-membered ring with a double bond and an OH (hydroxyl) group attached. - **Second molecule (middle):** - Comprises an amide group (NH₂) with a carbonyl group (C=O) attached. 2. **Reaction:** - These molecules react together, as indicated by the "+" and the arrow, to form a new product. 3. **Product:** - **Final molecule (right side):** - The benzene ring is still fused to the five-membered ring. - A NH₂ (amine) group replaces the initial OH group. This reaction shows the transformation of a hydroxyl group to an amine group within an indole framework, showcasing a common type of organic synthesis used in pharmaceutical chemistry and other chemical industries involving indole derivatives.
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